高瞻教授基于“既病防变”理论论治前列腺癌及其并发症经验

Professor Gao Zhan’s experience in the treatment of prostate cancer and its complications based on the theory of“prevent progression after disease onset”

本文总结高瞻教授基于“既病防变”理论论治前列腺癌及其并发症的诊疗经验。高瞻教授认为,对于前列腺癌,一是对于激素敏感性前列腺癌,宜祛邪为主、扶正为辅,清热活血解毒为主,辅以益气补脾,延长该期;对于去势抵抗性前列腺癌,扶正为主、祛邪为辅,兼以清热活血解毒,延缓全身转移,延长生存期。二是对于前列腺癌根治术后相关并发症如术后尿失禁、雄激素剥夺治疗后代谢并发症、围化疗期不良反应,基于“既病防变”理论的中医药治法能显著控制症状,改善不良反应。临床中,高瞻教授根据“既病防变”理论选择患者疾病所处不同阶段及涵盖并发症的合理治疗方案,对前列腺癌防治具有重要指导作用。

This article summarizes Professor Gao Zhan’s experience in the treatment of prostate cancer and its complications based on the theory of“prevent progression after disease onset”.Professor Gao Zhan believes that for prostate cancer,first of all,for hormone-sensitive prostate cancer,it is appropriate to eliminate pathogenic factor as the main,strengthening vital qi as a supplement,clearing heat,promoting blood,and detoxification as the main,supplemented by supplementing qi and replenishing the spleen to prolong the period;for castration-resistant prostate cancer,strengthening vital qi as the main,eliminate pathogenic factor as a supplement,and clearing heat,activating blood,and detoxification,delay systemic metastasis,prolong survival.Secondly,for the related complications after radical prostatectomy of prostate cancer,such as postoperative urinary incontinence,metabolic complications after androgen deprivation treatment,and adverse reactions during perichemotherapy,the traditional Chinese medicine treatment based on the theory of“prevent progression after disease onset”can significantly control symptoms and improve adverse reactions.In clinical practice,Professor Gao Zhan selects reasonable treatment plans for patients at different stages of disease and covering complications according to the theory of“prevent progression after disease onset”,which has an important guiding role in the prevention and treatment of prostate cancer.