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Preoperative Feeding in Single Ventricle Neonates is Predictive of Shorter Time to Goal Feed

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摘要 Background:Patients with single ventricle anatomy are at increased risk of growth failure and malnutrition.Amongst cardiac centers,there is little standardization of feeding practices in this complex population.We hypothesized that initiation of our center’s preoperative feeding protocol would result in decreased gastrostomy tube(G-tube)use,decreased length of stay and would not result in increased Necrotizing Enterocolitis(NEC)rates.Methods:A single institution review of 52 patients who had undergone stage I single ventricle palliative repair was performed.Patient diagnoses were hypoplastic left heart syndrome(39%),atrioventricular canal(15%),and other(46%).Postoperative parameters such as time to goal feed and need for gastrostomy tube(G-tube)were compared among preoperatively fed and non-preoperatively fed groups.Time to goal feed was calculated as time from first postoperative enteral feed to goal volume of 100 mL/kg.Results:Of the 26 patients who met inclusion criteria for preoperative feeding,22 patients(85%)were fed prior to surgery.Cox proportional hazard ratio revealed that age at surgery(p=0.047)and being preoperatively fed(p=0.001)were associated with reaching goal feed sooner.Multivariable analysis revealed that being preoperatively fed made a patient twice as likely to reach goal feed sooner(p=0.047).Univariable logistic regression revealed that days on total parenteral nutrition(p=0.018),length of hospitalization(p=0.008),and time to 1st postoperative feed(p=0.020)were significantly associated with higher odds of needing a G-tube postoperatively.Multivariable logistic regression did not show any predictors of postoperative G-tube usage.However,there was a trend towards lower G-tube usage in the preoperatively fed group.Conclusions:Implementing a standardized preoperative feeding protocol in single ventricle neonates can result in significantly shorter time to goal feed in preoperatively fed patients.It is beneficial for institutions to begin implementing standard feeding protocols to improve nutrition and growth outcomes.
出处 《Congenital Heart Disease》 SCIE 2022年第5期505-518,共14页 先天性心脏病(英文)
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