疏风止咳方治疗风盛挛急型感染后咳嗽临床疗效观察

Clinical therapeutic effect of the Shufeng Zhike decoction on post-infectious cough of the extensive wind and contracture syndrome

目的:探讨疏风止咳方治疗风盛挛急型感染后咳嗽(Postinfectious Cough,PIC)临床疗效。方法:研究对象为2018年9月-2019年9月就诊于北京市鼓楼中医医院内科门诊的PIC患者81例,均辨证为风盛挛急证。采用随机数字表法将其随机分为两组。治疗组42例中男性20例,女性22例。对照组39例中男18例,女21例。两组治疗前一般资料情况对比无显著性差异。对照组给予复方甲氧那明胶囊,每次2粒,每日3次。治疗组服用自拟疏风止咳方治疗。两组疗程均为10 d。观察治疗前后咳嗽症状积分、证候积分、视觉模拟评分法(Visual Analogue Scale,VAS)评分。结果:治疗组咳嗽症状积分、中医证候积分、VAS评分均优于对照组,差异有统计学意义。治疗组总有效率为88.1%(37/42),对照组总有效率为69.2%(27/42),治疗组总疗效好于对照组,差异有统计学意义。结论:疏风止咳方在中医整体辨证基础上治疗风盛挛急型PIC,在改善咳嗽症状、中医证候、VAS评分方面均优于西药治疗,且治疗期间未见明显不良反应,是治疗PIC的一种有效方法。

Objective:To study the effect of the Shufeng Zhike decoction(疏风止咳方)on post-infectious cough of the extensive wind and contracture syndrome.Methods:The study subjects were 81 patients with post-infection cough who attended the Internal Medicine Clinic of Beijing Gulou Hospital of Traditional Chinese Medicine from September 2018 to September 2019.All patients were with syndrome of extensive wind and contracture.The patients were randomly divided into two groups by the random number method.There were 42 cases in the TCM treatment group,including 20 males and 22 females.There were 39 cases in the control group,including 18 males and 21 females.There was no significant difference in the general data before treatment between the two groups.The control group was given compound methoxamine capsule,2 capsules each time,3 times a day.The treatment group was treated with the Shufeng Zhike decoction.The treatment course in both groups was 10 days.Cough symptom score,syndrome score and visual analogue scale(VAS)before and after treatment were observed.Results:The cough symptom score,TCM syndrome score and visual analog score in the treatment group were better than those in the control group,and the difference was statistically significant.The total effective rate in the treatment group was 88.1%(37/42),and that in the control group was 69.2%(27/39).The total curative effect in the treatment group was better than the control group,and the difference was statistically significant.Conclusion:The Shufeng Zhike decoction was superior to Western medicine treatment in ameliorating cough symptoms,TCM syndrome and visual analog score based on TCM overall syndrome differentiation,and no obvious adverse reactions were observed during the treatment,so it was an effective method for the treatment of cough after infection.