基于血浊理论从痰、瘀、毒论治缺血性脑卒中

Treatment of ischemic stroke from perspective of phlegm blood stasis and poison based on theory of turbid blood

血浊是缺血性脑卒中发病的病理基础,也是其进展、迁延、继发的致病因素。血浊与痰、瘀、毒作用于缺血性脑卒中发生发展的不同时期,又可相互兼夹、相互转化。血脂异常、高血糖、高同型半胱氨酸血症、氧化应激反应、炎症反应、内皮损伤等微观指标赋予“血浊”理论具体意义和临床应用价值。基于血浊理论从痰、瘀、毒角度探讨缺血性脑卒中的防治,可将宏观辨证与微观辨病有机结合,为缺血性脑卒中的中医防治提供微观落脚点。

Turbid blood is not only the pathological basis of onset of ischemic stroke,but also pathogenic factor of its disease progression,delayed healing,and secondary disease.Turbid blood,phlegm,blood stasis and poison play roles in different periods of ischemic stroke,affect each other and cause disease together.The existence of in vivo microscopic indicators such as dyslipidemia,hyperglycemia,hyperhomocysteinemia,oxidative stress response,inflammatory response,and endothelial injury endows the theory of turbid blood with specific significance and clinical application value.Based on the theory of turbid blood,discusses prevention and treatment of ischemic stroke from perspective of phlegm,blood stasis and poison.Organically combine macroscopic syndrome differentiation with microscopic disease differentiation,provide microscopic foothold for prevention and treatment of ischemic stroke.