经尿道膀胱癌二次电切治疗非肌层浸润膀胱癌的临床研究

Clinical study of transurethral bladder cancer secondary electrodesis for non-muscle invasive bladder cancer

目的分析经尿道膀胱癌二次电切治疗非肌层浸润膀胱癌患者的临床效果。方法选取2019年5月至2021年5月本院收治的60例膀胱癌患者(经临床诊断为非肌层浸润性)作为研究对象,按照治疗方法不同分为对照组和实验组,每组30例。对照组采用常规电切术治疗,观察组采用经尿道膀胱癌二次电切术治疗,比较两组健康相关生命质量(HRQOL)评分、导管留置时间、住院时间、术后并发症发生情况、复发情况及生存情况。结果治疗后,实验组生理状态、心理状态、社会功能、情感职能评分均高于对照组,差异有统计学意义(P<0.05)。实验组尿管留置时间及住院时间均短于对照组,差异有统计学意义(P<0.05)。实验组并发症发生率为3.33%,低于对照组的26.67%,差异有统计学意义(P<0.05)。术后1年随访,实验组复发率为3.33%,低于对照组的26.67%,差异有统计学意义(P<0.05)。两组均无死亡患者,安全系数高。结论采用经尿道膀胱癌二次电切治疗非肌层浸润膀胱癌效果显著,可有效改善患者临床症状,改善预后,值得临床推广应用。

Objective To analyze the clinical effect of secondary electroresection of transurethral bladder cancer in patients with non-muscleinvasive bladder cancer.Methods A total of 60 patients with bladder cancer(clinically diagnosed as non-muscle-invasive by clinical diagnosis)admitted to our hospital from May 2019 to May 2021 were selscted as the research subjects,and they were divided into control group and experimental group according to different treatment methods,with 30 cases in each group.The control group was treated with conventional electroresection,and the observation group was treated with secondary electroresection for transurethral bladder cancer,and the health-related quality of life(HRQOL)score,catheter indwelling time,hospital stay,postoperative complications,recurrence and survival were compared between the two groups.Results After treatment,the the scores of physiological state,psychological state,social function and emotional function in the experimental group were higher than those in the control group,and the differences were statistically significant(P<0.05).The urinary catheter indwelling time and hospital stay in the experimental group were shorter than those in the control group,and the differences were statistically significant(P<0.05).The complication rate in the experimental group was 3.33%,which was lower than 26.67%of the control group,and the differences were statistically significant(P<0.05).At 1 year follow-up after surgery,the recurrence rate in the experimental group was 3.33%,which was lower than 26.67%of the control group,and the difference was statistically significant(P<0.05).There were no fatal patients in either group,and the safety factor was high.Conclusion The secondary electroresection of transurethral bladder cancer in the treatment of non-muscle-invasive bladder cancer has a significant effect,which can effectively improve the clinical symptoms and prognosis of patients,which is worthy of clinical promotion and application.