倍他司汀联合祛痰活血止旋汤治疗良性阵发性位置性眩晕及脑动脉供血不足的临床疗效

Clinical efficacy of betahistine combined with expectorant and hemostatic decoction in the treatment of benign paroxysmal positional vertigo and cerebral arterial insufficiency

目的探讨倍他司汀联合祛痰活血止旋汤治疗良性阵发性位置性眩晕及脑动脉供血不足的临床疗效。方法选取2017年1月至2019年3月本院收治的78例良性阵发性位置性眩晕及脑动脉供血不足患者作为研究对象,并按照摸球法分为对照组和研究组,每组39例。对照组单纯采用倍他司汀治疗,研究组采用倍他司汀联合祛痰活血止旋汤治疗,比较两组临床疗效、治疗前后眩晕症状变化、凝血指标变化。结果研究组治疗总有效率为97.44%,高于对照组的79.50%,差异有统计学意义(P<0.05)。治疗前,两组眩晕障碍量表评分(DHI)、血浆纤维蛋白原FIB、D-二聚体(D-D)、血浆黏度、全血高切黏度、全血低切黏度、红细胞压积水平比较差异无统计学意义;治疗后,两组DHI评分、血浆纤维蛋白原FIB、D-D、血浆黏度、全血高切黏度、全血低切黏度、红细胞压积水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。结论倍他司汀联合祛痰活血止旋汤治疗良性阵发性位置性眩晕及脑动脉供血不足的临床疗效显著,可有效控制患者眩晕症状,调节凝血指标,改善血液流变学指标,值得临床推广应用。

Objective To investigate the clinical efficacy of betahistine combined with expectorant and hemostatic decoction in the treatment of benign paroxysmal positional vertigo and cerebral arterial insufficiency.Methods A total of 78 patients with benign paroxysmal positional vertigo and cerebral arterial insufficiency admitted to our hospital from January 2017 to March 2019 were selected as research subjects,and they were divided into control group and research group according to the ball touching method,with 39 cases in each group.The control group was treated with betagluptine alone,and the research group was treated with betataxine combined with expectorant and hemostatic decoction,and the clinical efficacy,changes in vertigo symptoms and coagulation indexes before and after treatment were compared between the two groups.Results The total clinical effective rate of the research group was 97.44%,which was higher than that of the control group(79.50%),and the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in vertigo disorder scale score(DHI),plasma fibrinogen FIB,D-dimer(D-D),plasma viscosity,whole blood high cut viscosity,whole blood low cut viscosity,and hematocrit levels;after treatment,the DHI score,plasma fibrinogen FIB,D-D,plasma viscosity,whole blood high cut viscosity,whole blood low cut viscosity,and hematocrit levels were lower than those before treatment,and the research group was lower than that of the control group,and the differences were statistically significant(P<0.05).Conclusion The clinical efficacy of betataxine combined with expectorant and hemostatic decoction in the treatment of benign paroxysmal positional vertigo and cerebral arterial insufficiency is outstanding,and it can effectively control the symptoms of vertigo,adjust coagulation indexes,and improve blood rheological indicators,which is worthy of clinical promotion and application.