音乐疗法联合文拉法辛治疗产后抑郁患者的临床疗效

Clinical efficacy of music therapy combined with venlafaxine in the treatment of postpartum depression

目的探讨音乐疗法联合文拉法辛治疗产后抑郁患者(PPD)的临床疗效。方法选取2019年7月至2020年12月本院收治的120例PPD患者作为研究对象,随机分为两组,每组60例。对照组给予文拉法辛治疗,观察组在对照组基础上联合音乐疗法治疗。比较两组爱丁堡产后抑郁量表(EPDS)评分、自觉压力[中文版压力知觉量表(CPSS)]及自我效能情况[一般自我效能感量表(GSES)]、不良反应发生情况。结果治疗后,两组EPDS评分均明显低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗后,两组CPSS评分均明显低于治疗前,GSES评分均明显高于治疗前,且观察组GSES评分明显低于对照组,GSES评分明显高于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率为11.67%,明显低于对照组的26.67%,差异有统计学意义(P<0.05)。结论音乐疗法联合文拉法辛治疗PPD临床疗效显著,可有效改善患者产后抑郁症状,降低自觉压力及不良反应发生率,提高自我效能感,值得临床推广应用。

Objective To explore the clinical efficacy of music therapy combined with venlafaxine in the treatment of postpartum depression(PPD).Methods 120 patients with PPD admitted to our hospital from July 2019 to December 2020 were selected as the research subjects,and they were randomly divided into two groups,with 60 patients in each group.The control group was treated with venlafaxine,and the observation group was treated with music therapy on the basis of the control group.The Edinburgh postnatal depression scale(EPDS)score,perceived stress(Chinese perceived stress scale[CPSS]),self-efficacy(general self-efficacy scale[GSES])and the occurrence of adverse reactions were compared between the two groups.Results After treatment,EPDS scores in both groups were significantly lower than before treatment,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).After treatment,CPSS score in both groups was significantly lower than before treatment,GSES score was significantly higher than before treatment,and GSES score in the observation group was significantly lower than control group,GSES score was significantly higher than the control group,the differences were statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 11.67%,which was significantly lower than 26.67%in the control group,and the difference was statistically significant(P<0.05).Conclusion Music therapy combined with venlafaxine in the treatment of PPD has significant clinical effect,which can effectively improve the symptoms of postpartum depression,reduce the perceived stress and the incidence of adverse reactions,and improve self-efficacy,which is worthy of clinical application.