生化检验指标应用于肝硬化疾病诊断中的意义分析

Analysis of the significance of biochemical test in the diagnosis of cirrhosis

目的探讨生化检验指标在肝硬化疾病诊断中的意义。方法选取2019年10月至2020年5月于本院治疗的51例肝硬化疾病患者作为实验组,另选取同期本院51名健康检查人员作为参照组,对所有研究对象均进行生化指标[白蛋白(ALB)、胆碱酯酶(CHE)、总胆红素(TBL)、直接胆红素(DBL)、冬氨酸转氨酶(AST)、总胆汁酸(TBA)、丙氨酸转氨酶(ALT)、碱性磷脂酶(ALP)]检验,比较两组生化指标检查结果。结果实验组ALB、CHE低于对照组,TBIL、DBIL、AST、TBA、ALT、ALP高于对照组,差异有统计学意义(P<0.05)。结论对肝硬化疾病患者采用生化项目检查创伤小、安全性较高,可为临床疾病准确治疗提供理论依据,降低肝硬化疾病误诊率,临床应用价值较高。

Objective To explore the significance of biochemical tests in the diagnosis of cirrhosis.Methods 51 patients with cirrhosis treated in our hospital from October 2019 to May 2020 were selected as the experimental group,and 51 health examiners from our hospital during the same period were selected as the reference group.Biochemical indices(albumin[ALB],cholinesterase[CHE],total bilirubin[TBL],direct bilirubin[DBL],partic aminotransferase[AST],total bile acid[TBA],alanine aminotransferase[ALT],alkaline phospholipase[ALP])were tested for all subjects,and the results of biochemical indices were compared between the two groups.Results ALB and CHE of the experimental group were lower than those of the control group,while TBIL,DBIL,AST,TBA,ALT and ALP of the experimental group were higher than those of the control group,the difference was statistically significant(P<0.05).Conclusion Biochemical examination for patients with cirrhosis has low trauma and high safety,which can provide theoretical basis for accurate treatment of clinical diseases,reduce the misdiagnosis rate of cirrhosis,and has high clinical application value.