半夏白术天麻汤加减联合高压氧对脑梗死后神经功能及血流动力学的影响

The effect of Banxia Baizhu Tianma decoction combined with hyperbaric oxygen on nerve function and hemodynamics after cerebral infarction

目的:观察中药半夏白术天麻汤加减联合高压氧治疗对脑梗死神经功能以及血液动力学指标的影响。方法:选取2018年1月至2020年1月防城港市中医医院收治的80例脑梗死患者展开研究,随机分为研究组和对照组,各40例,对照组实施高压氧治疗,研究组在对照组基础上加用半夏白术天麻汤加减治疗,对比两组患者的临床疗效及各项指标差异。结果:两组治疗后的风证、痰证、瘀证评分、血浆黏稠度、纤维蛋白原、Hcy、高切全血黏度、低切全血黏度水平、NIHSS评分均明显低于治疗前(P<0.05);研究组患者治疗后的风证、痰证、瘀证评分、血浆黏稠度、纤维蛋白原、Hcy、高切全血黏度、低切全血黏度水平、NIHSS评分显著低于对照组(P<0.05);研究组的总有效率、1年生存率明显高于对照组(P<0.05);两组的不良反应发生率均为2.50%,差异无统计学意义(P>0.05)。结论:脑梗死患者应用中药半夏白术天麻汤加减联合高压氧治疗,可以改善患者的脑部血循环,改善患者神经功能以及中医症状,减轻组织炎症反应,降低治疗风险,延长患者的生存周期,值得临床推广。

Objective:To observe the effect of the modified treatment of Banxia Baizhu Tianma decoction combined with hyperbaric oxygen treatment on the neurological function and hemodynamics indexes of cerebral infarction.Methods:80patients with cerebral infarction admitted to our hospital from January 2018to January 2020were selected for this study and randomly divided into the study group and the conventional group,with 40patients in each group.The study group was treated with hyperbaric oxygen+Banxia Xiexin Decoction,while the conventional group was treated with hyperbaric oxygen.Compare the clinical efficacy and indicators of the two groups of patients.Results:After treatment,the traditional Chinese medicine syndrome points,plasma viscosity,fibrinogen,Hcy,high whole blood viscosity,low whole blood viscosity and NIHSS score in both groups were significantly lower than those before treatment(P<0.05);After treatment,the scores of wind syndrome,phlegm syndrome,stasis syndrome,plasma viscosity,fibrinogen,Hcy,high whole blood viscosity,low whole blood viscosity,NIHSS score in the study group were significantly lower than those in the conventional group(P<0.05);The total effective rate and 1-year survival rate of the study group were significantly higher than those of the conventional group(P<0.05);The incidence of adverse reactions in both groups was 2.50%(P<0.05).Conclusion:In patients with cerebral infarction,the application of traditional Chinese medicine Banxia Baizhu Tianma decoction combined with hyperbaric oxygen treatment can improve the cerebral blood circulation,the neurological function and symptoms of traditional Chinese medicine,reduce tissue inflammation,reduce the risk of treatment and prolong the survival cycle of patients,which is worthy of clinical promotion.