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英夫利昔单抗在类固醇难治性溃疡性结肠炎中的临床应用效果

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摘要 目的:分析类固醇难治性溃疡性结肠炎患者应用英夫利昔单抗治疗的临床效果。方法:选择2018年1月至2019年8月于本院进行诊治的类固醇难治性溃疡性结肠炎患者,人数为92例,基于单盲分组法将其分为参照组与研究组,每组人数为46例,参照组对患者施以的治疗方式为硫唑嘌呤,观察组在参照组基础上应用英夫利昔单抗,对比两组患者的临床治疗有效率、血清炎症因子水平以及临床症状评分。结果:研究组临床治疗有效率明显高于参照组的数据,比较存在显著优势(P<0.05);研究组患者在血清炎症因子水平方面的数据显著低于参照组(P<0.05);研究组患者Mayo评分显著低于参照组。结论:类固醇难治性溃疡性结肠炎患者应用英夫利昔单抗治疗方式,可以提升患者临床治疗的效果,降低患者炎症因子的指标,并有效改善患者临床症状,对患者预后具有重要意义。
作者 庄文侠
出处 《中外女性健康研究》 2023年第12期40-42,共3页 Women's Health Research
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