摘要
原发性甲状旁腺功能亢进症(PHPT)是一种常见的内分泌疾病,通常由甲状旁腺功能亢进引起。手术切除功能亢进的病灶是治疗PHPT的主要手段,正确定位病灶对于指导PHPT患者的微创手术治疗至关重要。PET/CT目前已经成为甲状旁腺腺瘤术前定位的一线影像学手段,而如何从血清生化水平筛选出适合行PET/CT的患者成为临床应用的重点,从组织病理学和免疫组化水平分析其与PET相关参数的关系也是目前研究的热点。笔者主要就PHPT患者的血清生化水平、组织病理学信息、免疫组化与PET/CT相关参数之间的关系进行分析,并介绍了PHPT术前定位的影像学新进展,以期为PET/CT的临床应用提供指导。
Primary hyperparathyroidism(PHPT)is a common endocrine disease,which is usually caused by hyperparathyroidism.Surgical resection of hyperfunctional lesions is the main treatment for PHPT,and correct location of the lesions is very important to guide the minimally invasive surgical treatment of PHPT patients.PET/CT has been used as the first-line imaging method for preoperative localization of parathyroid adenoma,and how to screen the patients suitable for PET/CT from the serum biochemistry has become the focus of clinical application,as well as the analysis of its relationship with PET related parameters from the level of pathology and immunohistochemistry is the focus of current research.This article mainly analyzes the relationship between biochemical level,pathological information,immunohistochemical analysis and PET/CT related parameters of PHPT,providing guidance for the clinical application of PET,and further introducing the new imaging progress of preoperative localization of PHPT.
作者
赵宇嘉
白侠
Zhao Yujia;Bai Xia(The First Clinical College of Inner Mongolia Medical University,Huhhot 010050,China;Department of Nuclear Medicine,Affiliated Hospital of Inner Mongolia Medical University,Key Laboratory of Molecular Imaging of Inner Mongolia,Huhhot 010050,China)
出处
《国际放射医学核医学杂志》
2023年第4期243-248,共6页
International Journal of Radiation Medicine and Nuclear Medicine
基金
内蒙古自治区科技计划项目(RZ2100002963)。
