常克教授治疗儿童变应性鼻炎用药规律数据挖掘

Data mining of medication rules of Professor Chang Ke in the treatment of allergic rhinitis in children

目的分析常克教授治疗儿童变应性鼻炎的用药规律,总结其治疗变应性鼻炎的思路。方法收集常克教授2020年9月1日至2022年10月1日门诊治疗变应性鼻炎的处方,将处方的药物名称规范化,在古今医案云平台建立数据库,采用多种分析方法,对收集的数据进行多角度分析,挖掘常克教授治疗变应性鼻炎的用药规律。结果共纳入处方824首,284味中药。经过古今医案云平台数据分析,得出高频药物为蝉蜕、黄芩、苍耳子、辛夷、知母等,药性多寒、温、微寒、平,药味甘、苦、辛、淡,归经主要为肺经、胃经和肝经。用药功效以清热解毒、疏散风热、利咽类药物为主。聚类分析得到5组药物,复杂网络分析得到10味核心药物。结论常克教授治疗变应性鼻炎以“祛邪”为主要思想,善用通鼻窍,疏风清热,清热燥湿以及清热解毒中药。

Objective To analyze the medication rules of Professor Chang Ke in the treatment of allergic rhinitis in children,and summarize his thoughts on the treatment for allergic rhinitis.Methods Collect the prescriptions of Professor Chang Ke for the treatment of allergic rhinitis in the outpatient department from September 1,2020 to October 1,2022,standardize the drug names in the prescriptions,establish a database on the ancient and modern medical record cloud platform,and use multiple analysis methods to analyze the collected data from multiple perspectives,in order to explore the drug use rules of Professor Chang Ke in the treatment of allergic rhinitis.Results A total of 824 prescriptions and 284 traditional Chinese medicines were included.According to the analysis of the data from the cloud platform of ancient and modern medical records,it is concluded that the high-frequency drugs were cicada slough,scutellaria baicalensis,Xanthium sibiricum,Magnolia magnolia,Anemarrhena asphodeloides,etc.The drug properties were mainly cold,warm,slightly cold and flat,and the medicine tastes sweet,bitter,spicy and light,and the meridians involved were mainly the lung,stomach and liver meridians.The main types of drugs were antipyretic and detoxifying drugs,wind-heat evacuation drugs and pharynx-benefiting drugs.Five groups of drugs were obtained by cluster analysis,and 10 core drugs were obtained by complex network analysis.Conclusion Professor Chang Ke treats allergic rhinitis mainly based on"removing pathogenic factors".He is good at using traditional Chinese medicine to clear the nose,expel wind and heat,reduce heat and dry dampness,and remove heat and toxin.