芳香疗法并一贯煎治疗肾虚肝郁型经断前后诸证的临床疗效

A Clinical Study on the Treatment of Kidney Deficiency and Liver Depression before and after Jingduan by Aromatherapy Combined with Yiguanjian

目的观察芳香疗法并一贯煎治疗对肾虚肝郁型经断前后诸证的临床疗效。方法本论文选取符合纳入标准的经断前后诸证肾虚肝郁型患者60例,随机分为对照组和治疗组,30例/组。对照组给予一贯煎口服治疗,治疗组在口服一贯煎基础上给予真薰衣草精油局部外用。2组治疗周期均为1个月。采用肾虚肝郁型经断前后诸证评分表、匹兹堡睡眠质量指数表(PSQI)、改良Kupperman评分表(KMI)、汉密尔顿焦虑量表(HAMA)对经断前后诸证肾虚肝郁型患者进行观察。结果2组患者在中医证候疗效、PSQI单症状和总积分、Kupperman单症状(除对照组神经过敏和焦虑症状外)、汉密尔顿焦虑量表积分中较治疗前均有降低(P<0.05),且治疗组在PSQI中的总积分、Kupperman中的失眠、神经过敏、焦虑、忧郁症状积分、汉密尔顿焦虑量表积分优于对照组(P<0.05);治疗组睡眠疗效优于对照组,差异具有统计学意义(P<0.05);治疗组临床总有效率83.33%,对照组临床总有效率73.33%,2组比较差异有统计学意义(P<0.05)。结论在一贯煎基础上加用芳香疗法能提高患者中医证候疗效、改善睡眠质量、更年期综合征及焦虑状态,且优于单纯一贯煎口服,可在临床推广应用。

Objective To observe the clinical effect of aromatherapy combined with Yiguanjian on sleep and anxiety of syndromes of kidney deficiency and liver depression before and after Jingduan.Methods In this project,60 cases of patients with kidney deficiency and liver depression who met the inclusion criteria before and after Jingduan were randomly divided into a control group and a treatment group,30 cases in each group.The control group was given oral treatment of Yiguanjian,the treatment group was given topical application of true lavender essential oil plus oral treatment of Yiguanjian.The treatment period of the two groups was one month.The patients with syndromes of kidney deficiency and liver stagnation before and after Jingduan were observed with the score scale of syndromes of kidney deficiency and liver depression,Pittsburgh sleep quality index(PSQI),modified Kupperman scale(KMI),and Hamilton anxiety scale(HAMA).Results The curative effect of TCM symptoms,PSQI single symptom and total score,Kupperman single symptom(except nervousness and anxiety symptoms in the control group),and Hamilton anxiety scale scores of the two groups were lower than those before treatment(P<0.05).Moreover,the total score of PSQI,the score of insomnia,nervousness,anxiety,depression symptoms and Hamilton anxiety scale score of the treatment group were better than those of the control group(P<0.05);the sleep effect of the treatment group was better than that of the control group,with statistical significance clinical significance(P<0.05);the total clinical effective rate of the treatment group was 83.33%,and that of the control group was 73.33%,and the difference between the two groups was statistically significant(P<0.05).Conclusion Adding aromatherapy on the basis of Yiguanjian can improve the curative effect of TCM syndromes,improve sleep quality,menopausal syndrome and anxiety state,and it is better than oral administration of Yiguanjian alone.It can be popularized and applied in clinic.