肿瘤患者镇痛药物素养评估问卷的编制及信效度检验

Development and validation of Analgesic Medication Literacy Assessment Questionnaire for Cancer Patients

目的编制肿瘤患者镇痛药物素养评估问卷,为我国肿瘤患者提供有效的镇痛药物素养测评工具。方法以国际专家共识达成的药物素养定义及内涵为理论指导,通过文献回顾、患者半结构式深入访谈、德尔菲专家函询、预调查后形成问卷初稿。采用便利抽样法,对502例镇痛治疗期间的肿瘤疼痛患者进行问卷调查,对问卷进行项目分析及信效度检验。结果肿瘤患者镇痛药物素养评估问卷共29个条目,探索性因子分析共提取4个公因子,累积方差贡献率为71.978%,验证性因子分析各拟合指标均在可接受范围(χ^(2)/df=1.613,RMSEA=0.050,IFI=0.961,CFI=0.961);总问卷Cronbach′sα系数为0.940,折半信度为0.831,重测信度为0.884;问卷总的内容效度指数为0.957。结论编制的肿瘤患者镇痛药物素养评估问卷具有良好的信效度,可作为评估肿瘤患者镇痛药物素养水平的测评工具。

Objective To develop the Analgesic Medication Literacy Assessment Questionnaire for Cancer Patients,and to provide a valid tool for assessment of analgesic medication literacy in cancer patients in China.Methods Based on the definition of medication literacy reached by International experts and its connotation,a draft questionnaire was formed through literature review,semi-structured in-depth interviews with patients,Delphi expert consultation and pilot-testing.Then convenience sampling was adopted to select 502 patients on analgesic therapy for cancer pain for questionnaire survey.Item analysis and reliability and validity testing of the questionnaire were performed.Results The questionnaire comprised 4 dimensions totaling 29 items.Four common factors were extracted by exploratory factor analysis,and the cumulative variance contribution of the factors was 71.978%.Confirmatory factor analysis showed that the model structure fitted well(χ^(2)/df=1.613,RMSEA=0.050,IFI=0.961,CFI=0.961).The Cronbach′sαcoefficient of the whole questionnaire was 0.940,the split-half reliability coefficient was 0.831,and the test-retest reliability coefficient was 0.884.The scale-level content validity index of the questionnaire was 0.957.Conclusion The Analgesic Me-dication Literacy Assessment Questionnaire for Cancer Patients has good reliability and validity,and it can be used as an evaluation tool measuring cancer patients′analgesic medication literacy.