进食时机对尿毒症血液透析患者影响的研究

Influence study of eating timing on uremic hemodialysis patients

目的探讨进食时机对尿毒症血液透析患者的影响,为临床上此类研究提供参考依据。方法选取2018年5月—2020年5月于我院进行血液透析的患者42例,根据自身随机对照法分为A组(n=21)和B组(n=21)。A组患者前六次在血液透析1.5 h时进食,后六次在血液透析2.5 h时进食;B组患者前六次在血液透析2.5 h时进食,后六次在血液透析1.5 h时进食。观察比较1.5 h和2.5 h进食的患者在血液透析前以及血液透析中不同时间点的血压和血糖。结果2组患者在不同时间点的血压值和低血压发生率比较差异无统计学意义(P>0.05);血液透析1.5 h进食患者在透析2 h和3 h时血糖值明显高于2.5 h进食患者,比较差异具有统计学意义(P<0.05);血液透析1.5 h进食的患者在透析2 h时低血糖的发生率显著低于2.5 h进食患者,差异具有统计学意义(P<0.05)。结论对尿毒症血液透析患者来说,于血液透析1.5 h进食能够有效降低患者低血压和低血糖的发生几率。

Objective To discuss the influence of eating timing on uremic hemodialysis patients,and to provide a reference for this kind of clinical research.Methods A total of 42 patients undergoing hemodialysis were selected in our hospital from May 2018 to May 2020 and were divided into group A(n=21)and group B(n=21)according to self randomized control method.Patients in group A ate at 1.5 hour of hemodialysis for the first six times,and at 2.5 hour of hemodialysis for the last six times;patients in group B ate at 2.5 hour of hemodialysis for the first six times,and at 1.5 hour of hemodialysis for the last six times.Observed and compared the blood pressure and blood sugar of patients who eat at 1.5 hour and 2.5 hour before hemodialysis and at different time points during hemodialysis.Results There were no significant differences in blood pressure and the incidence of hypotension between the two groups of patients at different time points(P>0.05);the blood glucose levels at 2 and 3 hour of the patients who ate at 1.5 hour of hemodialysis was significantly higher than that of the patients who ate at 2.5 hour,and the difference was statistically significant(P<0.05);the incidence of hypoglycemia at 2 hour of hemodialysis in patients who ate at 1.5 hour was significantly lower than that of patients who ate at 2.5 hour,and the difference was statistically significant(P<0.05).Conclusions For uremic hemodialysis patients,eating at 1.5 hour of hemodialysis could effectively reduce the incidence of hypotension and hypoglycemia.