盐酸奈福泮注射液与输液配伍稳定性研究

Study on the Compatible Stability of Nefopam Hydrochloride Injection and Infusion

目的:研究盐酸奈福泮注射液与输液配伍的稳定性。方法:将盐酸奈福泮注射液分别用0.9%氯化钠注射液和5%葡萄糖注射液稀释,在25℃下于0,2,4,6,8,10,12,24 h内的稳定性。结果:在上述条件下,各项指标均较稳定。结论:盐酸奈福泮注射液与0.9%氯化钠注射液和5%葡萄糖注射液配伍后,在25℃条件下,24 h内稳定。

Objective:To study the stability of nefopam hydrochloride injection and infusion.Methods:Nefopam hydrochloride injection was diluted with 0.9%sodium chloride injection and 5%glucose injection respectively.The stability of nefopam hydrochloride injection was determined at 25℃within 0,2,4,6,8,10,12 and 24 hours.Results:All indexes were stable under the above conditions.Conclusion:Nefopam hydrochloride injection is stable within 24 hours at 25℃after compatibility with 0.9%sodium chloride injection and 5%glucose injection.