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定坤丹治疗肾虚肝郁证月经过少临床观察 被引量:1

Clinical Observation on Dingkun Mini-pill in the Treatment of Hypomenorrhea of Kidney Deficiency and Depressed Liver Syndrome
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摘要 目的 探讨与常规激素药物治疗相比,定坤丹治疗肾虚肝郁证月经过少的效果。方法 按随机双盲法将2019年1月—2022年1月就诊于黎川县中医医院的98例肾虚肝郁证月经过少患者分为2组,各49例。对照组接受戊酸雌二醇片治疗,研究组采用定坤丹治疗,均治疗1个疗程。对比2组疗效、月经出血量、性激素水平与子宫内膜厚度。结果 研究组治疗总有效率高于对照组(P<0.05);研究组治疗后血块积分、血染面积积分、月经出血量积分均高于对照组(P<0.05);研究组治疗后卵泡刺激素(FSH)、黄体生成素(LH)低于对照组,孕酮(P)、雌二醇(E_(2))、子宫内膜厚度高于对照组(P<0.05)。结论 与激素治疗相比,定坤丹在提高肾虚肝郁证月经过少的总疗效、增加月经量与子宫内膜厚度、改善性激素方面更具优势。 Objectivee To explore the effect of Dingkun mini-pill on menorrhagia in patients with kidney deficiency and liver depression compared with conventional hormone therapy.Methods A total of 98 patients who visited Lichuan Hospital of Traditional Chinese Medicine from August 2019 to September 2022 for hypomenorrhea due to kidney deficiency and liver stagnation were divided into two groups,with 49 cases in each group,according to the random double-blind method.The control group was treated with estradiol valerate tablets,and the study group was treated with Dingkun mini-pill for one course.The efficacy,menstrual bleeding,sex hormone levels and endometrial thickness were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group(P<0.05).The blood clot score,stained area score and monthly blood loss score of the study group were higher than those of the control group after treatment(P<0.05).Follicle stimulating hormone(FSH)and luteinizing hormone(LH)were lower than those in control group,while progesterone(P),estradiol(E_(2))and endometrial thickness were higher than those in control group after treatment(P<0.05).Conclusion Compared with hormone therapy,Dingkun mini-pill has more advantages in increasing the total curative effect of hypomenorrhea due to kidney deficiency and liver stagnation,increasing the menstrual flow and endometrial thickness,and improving sex hormones.
作者 杨平 YANG Ping(Department of Obstetrics and Gynecology,Lichuan Hospital of Traditional Chinese Medicine,Jiangxi Province,Lichuan 344600,China)
出处 《光明中医》 2023年第14期2765-2768,共4页 GUANGMING JOURNAL OF CHINESE MEDICINE
关键词 肾虚肝郁证 月经过少 定坤丹 中医药疗法 kidney deficiency and depressed liver syndrome hypomenorrhea Dingkun mini-pll therapy of TCM
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