基于麦醇溶蛋白递送体系研究进展

Research Progress Based on Gliadin Delivery Systems

麦醇溶蛋白,作为从小麦中提取得到的醇溶谷蛋白,因其良好的生物相容性、疏水性、微极性、胶黏性以及修饰和增强功能成分释放的能力,使其成为众多功能成分的潜在载体。本文对麦醇溶蛋白的结构、麦醇溶蛋白基载体的制备方法(反溶剂沉淀法、pH循环法、溶剂蒸发法、静电喷雾法、非静电络合法)及其在各类功能成分(抗氧化剂、酶、维生素、抗生素)递送中应用进行综述,并对不同制备方法的优缺点进行比较,以期为不同应用需求下麦醇溶蛋白递送体系的制备、拓展、开发以及为麦醇溶蛋白递送体系在食品、医药、生物骨架等方面的应用提供理论基础。

Gliadins,as prolamins extracted from wheat,have become potential promising carriers of multitudinous functional components due to their excellent biocompatibility,hydrophobicity,micropolarity,tackiness and ability to modify and enhance the release of functional components.This paper reviews the structure of gliadin,the preparation methods of gliadin-based carriers(antisolvent precipitation methods,pH-cycle methods,solvent evaporation methods,electrospraying methods,non-electrostatic complexation methods)and their applications in the delivery of a wide range of functional components(antioxidants,enzymes,vitamins,antibiotics),further more compares the corresponding advantages and disadvantages of each,in the hope of providing a theoretical basis for the preparation,expansion and development of gliadin delivery systems under different application requirements,as well as the applications of gliadin delivery systems in food,medicine,biological skeleton,etc.