妊娠期缺铁性贫血患者口服琥珀酸亚铁治疗的临床效果分析

Clinical Effect Analysis of Oral Ferrous Succinate Therapy in Patients with Iron Deficiency Anemia During Pregnancy

目的探究口服琥珀酸亚铁治疗妊娠期缺铁性贫血的治疗效果。方法选取2021年2月—2022年2月菏泽市牡丹人民医院妇产科妊娠期缺铁性贫血患者60例,凭借抽签方式分组,考察组30例采用琥珀酸亚铁治疗,一般组30例采用硫酸亚铁治疗,对比两组治疗总有效率、不良反应发生率、不良妊娠结局发生率、血红蛋白、血清铁蛋白。结果考察组治疗总有效率为96.67%比一般组的73.33%更高,差异有统计学意义(χ^(2)=4.705,P<0.05),考察组不良反应发生率低于一般组,差异有统计学意义(P<0.05),考察组不良妊娠结局发生率相比于一般组更低,差异有统计学意义(P<0.05),治疗前,考察组血红蛋白、血清铁蛋白水平与一般组对比,差异无统计学意义(P>0.05),治疗后,考察组血红蛋白、血清铁蛋白高于一般组,差异有统计学意义(P<0.05)。结论琥珀酸亚铁治疗妊娠期缺铁性贫血效果确切,可提高机体血红蛋白水平,改善不良妊娠结局。

Objective To investigate the therapeutic effect of oral ferrous succinate in the treatment of iron deficiency anemia during pregnancy.Methods Sixty patients with iron deficiency anemia during pregnancy in the obstetrics and gynecology department of Mudan People′s Hospital of Heze from February 2021 to February 2022 were selected and divided by lottery.30 patients in the investigation group were treated with ferrous succinate,while 30 patients in the general group were treated with ferrous sulfate.The total effective rate,incidence of adverse reactions,rate of adverse pregnancy outcomes,hemoglobin and serum ferritin were compared between the two groups.Results The total effective rate of treatment in the investigation group was 96.67%higher than that in the general group(73.33%),the difference was statistically significant(χ^(2 )=4.705,P<0.05).The incidence of adverse reactions in the investigation group was lower than that in the general group,the difference was statistically significant(P<0.05).The adverse pregnancy outcome rate in the investigation group was lower than that in the general group,the difference was statistically significant(P<0.05).Before treatment,the hemoglobin and serum ferritin of the investigation group had no statistically significant difference compared with the general group(P>0.05);after treatment,the hemoglobin and serum ferritin of the investigation group were higher than that of the general group,the difference was statistically significant(P<0.05).Conclusion Ferrous succinate is effective in treating iron deficiency anemia during pregnancy,which can improve the body′s hemoglobin index and improve adverse pregnancy outcomes.