胎儿先天性心脏病产前筛查的研究进展

Research progress in prenatal screening of fetal congenital heart disease

先天性心脏病(congenital heart disease,CHD)具有发病率高、危害大、死亡率高等特点,是新生儿死亡的主要原因之一。因此,使用更有效的医学检测方法,尽早发现CHD胎儿,并进行全面的评估和适当的产前干预,对降低儿童的致残率和死亡率、提高人口素质、减轻家庭和社会负担尤为重要。本文就CHD流行病学、胎儿CHD筛查时机、CHD影像学检查、高危胎儿遗传学检查等研究进行一一阐述。

Congenital heart disease(CHD)is one of the main causes of neonatal death,which is characterized by high incidence rate,great harm and high mortality.Therefore,using more effective medical detection methods,early detection of CHD fetuses,comprehensive evaluation,and appropriate prenatal interventions are particularly important for reducing child disability and mortality rates,improving population quality,and reducing family and social burdens.This article elaborates on the epidemiology of CHD,timing of fetal CHD screening,imaging examination of CHD,and genetic examination of high-risk fetuses.