摘要
环状RNA(circRNAs)是一种广泛存在于真核生物中的非编码RNA,因特殊的共价闭合环状结构而具有高度的稳定性和保守性。慢性阻塞性肺疾病(COPD)是一种常见的呼吸系统疾病,已有研究表明,circRNAs通过多种渠道参与到COPD的发生、发展过程中,本文就circRNAs功能及其在COPD中的研究进展作一综述。
circRNAs are noncoding RNAs that are widely found in eukaryotes.They are highly stable and conserved due to the special covalent closed loop structures.Chronic obstructive pulmonary disease(COPD)is a common disease of respiratory system.circRNAs participate in the development of COPD through many signaling pathways.This study aims to review the function of circRNAs and its research progress in COPD.
作者
杨海福
耑冰
Yang Haifu;Zhuan Bing(Department of Respiratory Medicine,the Third Clinical Medical College affiliated to Ningxia Medical University(Ningxia Hui Autonomous Region People′s Hospital),Yinchuan 750000,China)
出处
《国际呼吸杂志》
2023年第6期626-631,共6页
International Journal of Respiration
基金
国家自然科学基金(82160017)。
关键词
肺疾病
慢性阻塞性
RNA
环状
炎症
烟雾
Pulmonary disease,chronic obstructive
RNAs,circular
Inflammation
Smog
