Mimics仿真辅助支气管镜冷冻治疗支气管结核的临床研究

Clinical Study of Mimics Simulation-assisted Bronchoscopic Cryotherapy in the Treatment of Bronchial Tuberculosis

目的:研究Mimics仿真辅助支气管镜冷冻治疗支气管结核的效果。方法:选取2020年1月-2022年6月九江市第三人民医院收治的68例支气管结核患者,采用随机数字表法将患者分为观察组(n=34)和参比组(n=34)。参比组采用支气管镜冷冻治疗,观察组采用Mimics仿真辅助支气管镜冷冻治疗。比较两组总有效率、深部痰菌转阴率及免疫功能指标。结果:治疗后观察组的总有效率高于参比组(P<0.05)。观察组治疗后深部痰菌转阴率高于参比组(P<0.05)。治疗后观察组CD3+、CD4+、CD4+/CD8+均高于参比组,观察组CD8+低于参比组(P<0.05)。结论:Mimics仿真辅助支气管镜冷冻较单一的支气管镜冷冻治疗对支气管结核患者的效果好,其可有效提高患者深部痰菌转阴率及免疫功能,可在临床上借鉴应用。

Objective:To study the effect of Mimics simulation-assisted bronchoscopic cryotherapy in the treatment of bronchial tuberculosis.Method:A total of 68 patients with bronchial tuberculosis admitted to Third People's Hospital of Jiujiang City from January 2020 to June 2022 were selected,they were divided into observation group(n=34)and reference group(n=34)by random number table method.The reference group received bronchoscopic cryotherapy,and the observation group received Mimics simulation-assisted bronchoscopic cryotherapy.The total effective rate,negative conversion rate of deep sputum and immune function indexes were compared between the two groups.Result:After treatment,the total effective rate in the observation group was higher than that in the reference group(P<0.05).The negative conversion rate of deep sputum in the observation group was higher than that in the reference group(P<0.05).After treatment,CD3+,CD4+,CD4+/CD8+in the observation group were higher than those in the reference group,and CD8+in the observation group was lower than that in the reference group(P<0.05).Conclusion:The application of Mimics simulation-assisted bronchoscopic cryotherapy has better effect on patients with bronchoscopy than single bronchoscopy cryotherapy,which can effectively improve the negative conversion rate of deep sputum and immune function of patients,and can be used for reference in clinical practice.