太极拳对康复期精神分裂症患者焦虑抑郁情绪的影响

Effect of Taijiquan on Anxiety and Depression in Patients with Schizophrenia Rehabilitation Period

目的:分析太极拳对康复期精神分裂症患者焦虑抑郁情绪的影响。方法:将2021年3—6月江西省精神病院收治的80例康复期精神分裂症患者采用随机数字表法分为研究组、对照组,各40例。对照组予以常规药物治疗、康复护理、参加普通工娱疗活动,研究组另予以24式简化太极拳训练,均连续治疗8周。对比两组临床疗效,治疗前后精神症状、焦虑抑郁情绪、血清相关指标、睡眠质量与生活质量。结果:研究组治疗总有效率高于对照组(P<0.05)。治疗后研究组阳性和阴性精神症状评定量表(PANSS)阴性症状、一般精神病理评分及总评分均低于对照组(P<0.05),两组阳性症状评分比较,差异无统计学意义(P>0.05)。治疗后研究组汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)得分均低于对照组(P<0.05)。治疗后,研究组血清脑源性神经营养因子(BDNF)、5-羟色胺(5-HT)水平均高于对照组,肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)水平均低于对照组(P<0.05)。治疗后研究组匹兹堡睡眠质量指数(PSQI)、精神分裂症患者生活质量量表(SQLS)得分均低于对照组(P<0.05)。结论:太极拳训练用于康复期精神分裂症患者中,可明显减轻其焦虑抑郁情绪,改善临床症状,调节神经递质和炎症因子水平,提高睡眠质量与生活质量。

Objective:To analyze the effect of Taijiquan on anxiety and depression in patients with schizophrenia rehabilitation period.Method:A total of 80 patients with schizophrenia rehabilitation period admitted to Jiangxi Provincial Psychiafric Hospital from March to June 2021 were divided into study group and control group according to random number table method,with 40 cases in each group.The control group was given routine drug treatment,rehabilitation nursing and participation in ordinary occupation recreational therapy activities,and the study group was also given 24 simplified Taijiquan training,all of which were treated continuously for 8 weeks.The clinical efficacy,before and after treatment of mental symptoms,anxiety and depression,serum related indexes,sleep quality and quality of life were compared between the two groups.Result:The total effective rate of study group was higher than that of control group(P<0.05).After treatment,the scores of negative syndrome,general psychopathology and the total score of positive and negative syndrome scale(PANSS)in the study group were lower than those in the control group(P<0.05),and there was no significant difference in the scores of positive syndrome between the two groups(P>0.05).After treatment,the scores of Hamilton anxiety scale(HAMA)and Hamilton depression scale(HAMD)in the study group were lower than those in the control group(P<0.05).After treatment,the levels of brain derived neurotrophic factor(BDNF)and 5-hydroxytryptamine(5-HT)in the study group were higher than those in the control group,and the levels of tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)in the study group were lower than those in the control group(P<0.05).After treatment,the scores of Pittsburgh sleep quality index(PSQI)and schizophrenia quality of life scale(SQLS)in the study group were lower than those in the control group(P<0.05).Conclusion:Taijiquan training can significantly reduce anxiety and depression,improve clinical symptoms,regulate the levels of neurotransmitters and inflammatory factors,and improve sleep quality and quality of life in patients with schizophrenia rehabilitation period.