子午流注择时耳穴贴压结合中医情志干预对围绝经期失眠患者睡眠质量、情绪状态及神经递质水平的影响

Effects of midnight-noon ebb-flow timing auricular point sticking combined with traditional Chinese medicine emotional intervention on sleep quality,emotional state and neurotransmitter level of patients with perimenopausal insomnia

目的探讨子午流注择时耳穴贴压结合中医情志干预在围绝经期失眠中的应用效果。方法按照随机数字表法将我院收治的90例围绝经期失眠患者分为对照组与观察组,各45例。对照组实施常规护理干预,观察组在对照组基础上实施子午流注择时耳穴贴压结合中医情志干预。比较两组的干预效果。结果干预后,观察组的匹兹堡睡眠质量指数(PSQI)、汉密尔顿焦虑量表(HAMA)及汉密尔顿抑郁量表(HAMD)评分低于对照组,简式睡眠信念和态度量表(DBAS-16)评分高于对照组(P<0.05)。干预后,观察组的5-羟色胺(5-HT)、神经肽Y(NPY)及P物质(SP)水平高于对照组(P<0.05)。结论子午流注择时耳穴贴压结合中医情志干预在围绝经期失眠中的应用效果较好,可改善患者的睡眠质量与情绪状态,调节5-HT、NPY及SP水平。

Objective To explore the application effect of midnight-noon ebb-flow timing auricular point sticking combined with traditional Chinese medicine emotional intervention in perimenopausal insomnia.Methods A total of 90 patients with perimenopausal insomnia admitted in our hospital were divided into control group and observation group according to the random number table method,with 45 cases in each group.The control group received routine nursing intervention,and the observation group received midnight-noon ebb-flow timing auricular point sticking combined with traditional Chinese medicine emotional intervention on the basis of the control group.The intervention effects of the two groups were compared.Results After intervention,the scores of Pittsburgh Sleep Quality Index(PSQI),Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD)in the observation group were lower than those in the control group,and the score of Brief Version of Dysfunctional Beliefs and Attitudes About Sleep(DBAS-16)was higher than that in the control group(P<0.05).After intervention,the levels of 5-hydroxytryptamine(5-HT),neuropeptide Y(NPY)and substance P(SP)in the observation group were higher than those in the control group(P<0.05).Conclusion Midnight-noon ebb-flow auricular point sticking combined with traditional Chinese medicine emotional intervention in perimenopausal insomnia has a better application effect,which can improve the sleep quality and emotional state of patients,and regulate the levels of 5-HT,NPY and SP.