白藜芦醇调控卵巢功能作用的研究进展

Research progress on regulation of resveratrol on ovarian function

白藜芦醇(RSV)是一种存在于植物中的抗毒素和抗氧化剂,属于非黄酮天然多酚类化合物,对机体可产生保护作用。近年来,RSV在卵巢方面作用的研究日益增多。在卵巢生理方面,RSV可参与卵泡发育、颗粒细胞增殖、胚胎发育等众多过程;在卵巢病理方面,RSV不仅对多囊卵巢综合征(PCOS)、卵巢过度刺激综合征(OHSS)等疾病的治疗发挥作用,而且影响不孕妇女的辅助生殖过程。本文将从RSV调控卵泡发育、排卵、颗粒细胞增殖、胚胎发育以及卵巢疾病和辅助生殖技术等方面进行综述,以期为相关疾病的预防和治疗提出新的思路。

Resveratrol(RSV)is a kind of antitoxin and antioxidant existing in plants,which belongs to non-flavonoid natural polyphenols and has protective effect on the body.In recent years,the research of the RSV effects on the ovaries has been increasing.In ovarian physiology,RSV can regulate many physiological events such as follicular development,granulosa cell proliferation,embryo development.In terms of ovarian pathology,RSV not only plays a role in the treatment of diseases such as polycystic ovary syndrome(PCOS),ovarian hyper-stimulation syndrome(OHSS)and other diseases,but also affects the assisted reproductive process of infertile women.This paper reviews the role of RSV in the regulation of follicular development,ovulation,granulosa cell proliferation,embryo development,ovarian diseases and assisted reproductive technology,in order to put forward new ideas for the prevention and treatment of related diseases.