绝经后女性骨质疏松症患者生活质量问卷的汉化及信效度检验

Localization and the reliability and validity of the Chinese version of ECOS-16 in the postmenopausal osteoporosis patients

目的 对骨质疏松症患者生活质量问卷(ECOS-16)进行本土化研究,并检验其信效度。方法 通过翻译-综合-回译-文化调适对ECOS-16进行汉化,采用便利抽样法对216例绝经后女性骨质疏松症患者进行调查。采用Cronbach’s α系数、重测信度评价问卷信度;采用结构效度、内容效度及已知族群效度评价其效度。结果 中文版ECOS-16问卷总的Cronbach’s α系数为0.909,重测信度为0.946。通过项目分析以及探索性因子分析提取出4个公因子(疼痛、躯体功能、心理功能和疾病恐惧感),16个条目,累积方差贡献率为83.761%;总问卷的内容效度指数(S-CVI)为0.902;骨折组与非骨折组ECOS-16得分差异存在统计学意义(P<0.05)。结论 中文版ECOS-16信效度良好,可用于绝经后女性骨质疏松症患者生活质量的评测。

Objective To translate and revise the Assessment of Health Related Quality of Life in Osteoporosis(ECOS-16),and test the reliability and validity of the Chinese version of ECOS-16 in the postmenopausal osteoporosis patients.Methods ECOS-16 was translated and revised following the procedure of translation-integrate-back translation-expert review.After having modified the questionnaire to adapt to Chinese culture,the reliability and validity of the questionnaire were tested in a convenient population of 216 postmenopausal patients.The reliability was evaluated by internal consistency Cronbach's α coefficient and test-retest reliability;and the validity was evaluated by exploratory factor analysis(EFA),content validity and known-group validity.Results The Chinese version of ECOS-16 includes 16 items,a total of four domains(pain,physical function,mental function and fear of illness).The Cronbach's α coefficient for the total questionnaire was 0.909 and test-retest reliability was 0.946.Principal component analysis resulted in a 4-factor structure explaining 83.761% of the total variance.The content validity index(S-CVI) was 0.902.There was a significant difference in ECOS-16 scores between the fracture group and the non-fracture group.Conclusion The Chinese version of ECOS-16 appears to possess adequate reliability and validity,and can be used for the evaluation of quality of life of postmenopausal osteoporosis patients.