摘要
We report a visible light promoted carbochloromethylation of 2-bromomethyl acrylate and N-arylmethacrylamide,and a series of trihalomethyl substituted allylic acid esters and indolone derivatives were synthesized.The reaction used common and inexpensive chloroform and tribromomethane as tri-halomethyl reagents,iodobenzene diacetate(PIDA)as an oxidant and Eosin Y as a photocatalyst.The reaction conditions are mild and the substrate scope is wide.
基金
We acknowledge the financial support from the National Natural Science Foundation of China(No.22061038,22067018,22101232)
the Key Talent Projects of Gansu Province([2019]39)
the Natural Science Foundation of Gansu(No.20YF3GA023,20JR5RA210).
