神经介入动脉取栓与静脉溶栓治疗急性脑梗死的疗效分析

Therapeutic Effect of Nerve Interventional Arterial Thrombectomy and Intravenous Thrombolysis on Acute Cerebral Infarction

目的探究急性脑梗死患者在治疗中应用神经介入动脉取栓与静脉溶栓治疗的作用。方法随机选取2021年6月—2022年6月南平市第一医院收治的80例急性脑梗死患者为研究对象,随机分组,其中对照组40例运用静脉溶栓治疗方案,观察组40例运用神经介入动脉取栓治疗方案,观察比较两组临床总有效率、临床指标、神经功能评分,以及不良事件发生率。结果观察组总有效率为95.00%,相较对照组的67.50%更高,差异有统计学意义(χ^(2)=9.928,P<0.05)。观察组患者活化凝血酶原时间、凝血酶原时间、凝血酶时间相较对照组更长,纤维蛋白原测定结果相较对照组更低,差异有统计学意义(P<0.05)。相较对照组,观察组患者治疗后1 d、7 d、2周神经功能评分更低,差异有统计学意义(P<0.05)。结论神经介入动脉取栓可显著提升急性脑梗死患者的临床疗效,使化凝血酶原时间等相关临床指标获得改善,有效降低神经功能缺损程度,减少治疗过程中不良事件,更利于患者疾病治疗。

Objective To explore the effect of nerve interventional thrombectomy and intravenous thrombolysis in the treatment of patients with acute cerebral infarction.Methods Eighty patients with acute cerebral infarction admitted to Nanping First Hospital from June 2021 to June 2022 were randomly selected as the research objects and randomly grouped.Among them,forty cases included in the control group were treated with intravenous thrombolysis,and forty cases included in the observation group were treated with nerve interventional arterial thrombectomy.The total clinical effectiveness,clinical indicators,neurofunction function scores and adverse event incidence statistics were observed and compared between the two groups.Results The total effective rate of the observation group was 95.00%,which was higher than that of the control group of 67.50%,the difference was statistically significant(χ^(2)=9.928,P<0.05).Compared with the control group,the activated prothrombin time,prothrombin time and thrombin time of the patients in observation group was longer,and the fibrinogen of the observation group was lower,the difference was statistically significant(P<0.05).The neurological function scores of patients in the observation group were lower than those of the control group at 1 d,7 d and 2 weeks after treatment,the difference was statistically significant(P<0.05).Conclusion Nerve interventional arterial thrombectomy can significantly improve the clinical efficacy of patients with acute cerebral infarction,improve the prothrombin time and other related clinical indicators,effectively reduce the degree of neurological impairment,reduce adverse events during treatment,and more conducive to the disease treatment of patients.