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Impact of simulated in vitro gastrointestinal digestion on bioactive compounds,bioactivity and cytotoxicity of melon (Cucumis melo L. inodorus) peel juice powder

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摘要 The objectives of this research work were to evaluate the effect of in vitro gastrointestinal digestion (GIT) on melon peel juice (MPJ) powder from fruit processing industry by-products,considering (i) the recovery and accessibility indexes,(ii) the changes on antioxidant activity,and (iii) the prebiotic effect.Throughout exposition to GIT conditions a decrease on the total phenolic content (TPC = 65.31%) and antioxidant activity by ABTS = 39.77% and DPPH = 45.91% were observed.However,these both parameters exhibited stable accessibility,accounting with 81.89%,76.55%,and 54.07% for TPC,ABTS and DPPH,respectively.After gastrointestinal digestion,the non-absorbed fraction exhibited a positive impact on the growth of Bifidobacterium and Lactobacillus strains,possibly associated with the high content of simple sugar (glucose and fructose).This fraction also showed to be safe on Caco-2 intestinal cells.These findings suggest that MPJ might be used as a potential food functional ingredient.
出处 《Food Bioscience》 SCIE 2022年第3期1358-1367,共10页 食品生物科学(英文)
基金 National Council of Science and Technology(CONACyT,Mexico)for PhD fellowship support granted to G´omez-García Ricardo the project MultiBiorefinery:Estrat´egias multiuso para a valorizaç˜ao de uma gama alargada de subprodutos agroflorestais e das pescas:Um passo em frente na criaç˜ao de uma biorrefinaria"financiado pelo Programa Operacional Competitividade e Internacionalizaç˜ao(POCI-01-0145-FEDER-016403)e pelo Programa Operacional Regional de Lisboa(LISBOA-01-0145-FEDER-016403) na sua componente FEDER e pela Fundaç˜ao para a Ciˆencia e Tecnologia,I.P.na componente nacional(SAICTPAC/0040/2015).
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