针对性心理干预对肺癌患者围化疗期癌因性疲乏、负性情绪、遵医行为及生活质量的影响

Effect of targeted psychological intervention on cancer-related fatigue,negative emotion,compliance behavior and quality of life in lung cancer patients during peri-chemotherapy

目的探讨针对性心理干预对肺癌患者围化疗期癌因性疲乏、负性情绪、遵医行为及生活质量的影响。方法根据围化疗期干预方法的不同将116例肺癌患者分为对照组和观察组,每组58例,对照组患者进行常规干预,观察组患者在对照组的基础上进行针对性心理干预。比较两组患者的癌因性疲乏[Piper疲乏修订量表(PFS-R)]、负性情绪[焦虑自评量表(SAS)、抑郁自评量表(SDS)]、遵医行为(依从性调查量表)及生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)]。结果干预后,两组患者认知、行为、躯体感知及情感评分均低于本组干预前,观察组患者认知、行为、躯体感知及情感评分均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者SAS、SDS评分均低于本组干预前,观察组患者SAS、SDS评分均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者心理、运动、饮食、药物遵医行为评分均高于本组干预前,观察组患者心理、运动、饮食、药物遵医行为评分均高于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者情绪功能、认知功能、社会功能及躯体功能评分均高于本组干预前,观察组患者情绪功能、认知功能、社会功能及躯体功能评分均高于对照组,差异均有统计学意义(P﹤0.05)。结论肺癌患者围化疗期予以针对性心理干预,可缓解患者的癌因性疲乏,改善患者的负性情绪,提高患者的遵医行为和生活质量。

Objective To explore the effect of targeted psychological intervention on cancer-related fatigue,negative emotion,compliance behavior and quality of life in lung cancer patients during peri-chemotherapy.Method A total of 116 lung cancer patients were divided into control group(n=58,received routine intervention)and observation group(n=58,received targeted psychological intervention on the basis of the control group)according to different intervention methods during peri-chemotherapy.The cancer-related fatigue[the revised Piper fatigue scale(PFS-R)],negative emotion[self-rating anxiety scale(SAS)and self-rating depression scale(SDS)],treatment compliance(compliance questionnaire)and quality of life[European Organization for Research and Treatment of Cancer quality of life questionnaire core 30(EORTC QLQ-C30)]were compared between the two groups.Result After the intervention,the cognitive,behavioral,somatic perception and emotional scores of the two groups were lower than those before the intervention(P<0.05),with lower scores in the observation group than those in the control group(P<0.05).After the intervention,the scores of SAS and SDS in the two groups were lower than those before the intervention(P<0.05),with lower scores in the observation group than those in the control group(P<0.05).After the intervention,the scores of psychology,exercise,diet,medication compliance of the two groups were higher than those before the intervention(P<0.05),with higher scores in the observation group than those in the control group(P<0.05).After the intervention,the scores of emotional function,cognitive function,social function and physical function in the two groups were higher than those before the intervention(P<0.05),with higher scores in the observation group than those in the control group(P<0.05).Conclusion Targeted psychological intervention in the peri-chemotherapy period of lung cancer patients can significantly relieve cancer-related fatigue,thereby improving the negative emotions,medication compliance and quality of life.