高丰度稀土中熵陶瓷粉体的制备及抗菌性能研究

Preparation of High Abundance Rare Earth Medium Entropy Ceramic Powder and Its Antibacterial Properties

在新冠肺炎全球蔓延的背景下,人们对功能性抗菌材料提出了更高的要求,本文采用高温固相合成法制备了(La_(0.25)Sm_(0.25)Eu_(0.25)Gd_(0.25))_(2)W_(3)O_(12)和(La_(0.25)Sm_(0.25)Eu_(0.25)Gd_(0.25))_(2)O_(3)中熵陶瓷粉体。在黑暗条件下,对两种陶瓷粉体的抗大肠杆菌(革兰氏阴菌)和金色葡萄球菌(革兰氏阳菌)的性能进行测试,同时辅以XRD、EDS、TEM、粒度分析、离子溶出性实验和Zeta电位测试对合成产物进行表征。结果表明,合成产物元素分布均匀、粒度较小。两种中熵陶瓷粉体对两类细菌的抗菌率均大于99%,说明材料具有广谱抗菌性能。其中,中熵化后的材料能有效提高陶瓷粉体对大肠杆菌的抗菌活性,综合比较下,(La_(0.25)Sm_(0.25)Eu_(0.25)Gd_(0.25))_(2)W_(3)O_(12)抗菌性能优于(La_(0.25)Sm_(0.25)Eu_(0.25)Gd_(0.25))_(2)O_(3)。离子溶出性实验和Zeta电位测试显示,两种中熵陶瓷粉体表面带正电,在中性、强酸和强碱环境下离子溶出度低,表明材料为非离子溶出型抗菌剂。综上所述,新型中熵陶瓷粉体具有广谱抗菌性能,环境适应性高,可用于极端条件抗菌。

In the context of the global spread of neocrown pneumonia,there is a higher demand for functional antimicro⁃bial materials.In this paper,(La_(0.25)Sm_(0.25)Eu_(0.25)Gd_(0.25))_(2)W_(3)O_(12)and(La_(0.25)Sm_(0.25)Eu_(0.25)Gd_(0.25))_(2)O_(3)mesoentropic ceramic pow⁃ders were prepared by high⁃temperature solid⁃phase synthesis method,and the anti⁃Escherichia coli(Gram⁃negative bacteria)and Staphylococcus aureus(Gram⁃positive bacteria)properties of both ceramic powders were tested.The synthesized products were also characterized by XRD,EDS,TEM,particle size analysis,ion solubility test and zeta potential test.The results show that the synthesized products have uniform elemental distribution and small particle size.The antibacterial rates of the two mes⁃entropic ceramic powders were greater than 99%against both types of bacteria,indicating that the materials have broad⁃spec⁃trum antibacterial properties.Among them,the material after medium entropy can effectively improve the antibacterial activity of ceramic powder against Escherichia coli,and the antibacterial performance of(La_(0.25)Sm_(0.25)Eu_(0.25)Gd_(0.25))_(2)W_(3)O_(12)is better than that of(La_(0.25)Sm_(0.25)Eu_(0.25)Gd_(0.25))_(2)O_(3) in a comprehensive comparison.Ion solubility experiments and zeta potential tests show that the two mesentropic ceramic powders are positively charged on the surface and have low ion solubility in neutral,strong acid and strong base environments,indicating that the materials are non⁃ion soluble antimicrobial agents.In summary,the new mesentropic ceramic powders have broad⁃spectrum antibacterial properties and high environmental adaptability,and can be used for antibacterial in extreme conditions.