控制营养状态评分在乙肝肝硬化中的临床价值

Clinical value of CONUT score in hepatitis B cirrhosis

目的 基于控制营养状态(CONUT)评分,探讨肝硬化患者中营养不良情况,并分析该评分与乙肝肝硬化患者临床指标之间的关系。方法 以2020年1月至2022年8月在山东大学齐鲁医院住院的298例乙肝相关肝硬化患者为研究对象,回顾性收集患者入院后的首次检验资料,以CONUT评分评估患者的营养状况,与以体质量指数(BMI)、白蛋白(ALB)为标准的评估情况进行对比。结果 应用CONUT评分,298例肝硬化患者存在不同程度的营养不良,其中轻度营养不良的有68例(22.82%),中度营养不良的有176例(59.06%),重度营养不良的有54例(18.12%);在不同Child分级中,CONUT评分的分布差异有统计学意义。结论 肝硬化患者存在不同程度的营养不良,CONUT评分与肝硬化患者的临床分级严重程度密切相关,并且可以指导临床治疗。

Objective To explore malnutrition in patients with hepatitis B cirrhosis based on the controlling nutritional status(CONUT) score,and to analyze the relationship between CONUT score and clinical markers.Methods A total of 298 patients with hepatitis B cirrhosis treated in Qilu Hospital of Shandong University during Jan.2020 and Aug.2022 were selected.The first examination data after admission were collected,and the nutritional status was evaluated with CONUT score,which was compared with the results based on body mass index(BMI) and albumin(ALB).Results Based on CONUT score,all patients had different degrees of malnutrition,including 68 cases(22.82%) of mild malnutrition,176 cases(59.06%) of moderate malnutrition,and 54 cases(18.12%) of severe malnutrition.There were statistically significant differences in CONUT score among patients with different Child grades.Conclusion There are different degrees of malnutrition in patients with liver cirrhosis.The CONUT score is closely related to the severity of liver cirrhosis,and can guide clinical treatment.