^(18)F-FDG SPECT/CT对冠脉慢性完全闭塞性病变患者心肌代谢与侧支循环形成的诊断价值

Diagnostic value of ^(18)F-FDG SPECT/CT on myocardial metabolism and collateral circulation formation in patients with coronary chronic total occlusion

目的 探究冠脉慢性完全闭塞性病变患者18氟-脱氧葡萄糖双探头复合线路单光子计算机断层显像术(^(18)F-FDG SPECT/CT)心肌代谢与侧支循环形成的诊断价值。方法 回顾2018年1月~2022年12月我院收治的冠脉慢性完全闭塞性病变患者93例,所有患者均接受^(18)F-FDG SPECT/CT检查、冠状动脉造影检查,比较不同侧支循环形成程度、心肌存活情况、心肌存活与侧支循环形成的相关性。结果 93例冠脉慢性完全闭塞性病变患者,病变血管115支,不同侧支循环形成患者一般资料、心肌存活患者占比,差异无统计学意义(P>0.05),存活心肌面积、梗死心肌面积,差异有统计学意义(P<0.05);Spearman相关性分析显示,存活心肌面积、梗死心肌面积与Rentrop评分无相关性(P>0.05)。结论 冠脉慢性完全闭塞性病变患者侧支循环形成程度与心肌存活无关,术前进行^(18)F-FDG SPECT/CT心肌代谢显像确认存活心肌范围有重要价值。

Objective:To explore the diagnostic value of ^(18)F-fluorodeoxyglucose single-photon emission computed tomography/computed tomography(^(18)F-FDG SPECT/CT)on myocardial metabolism and collateral circulation formation in patients with coronary chronic total occlusion.Methods:93 patients with coronary chronic total occlusion admitted to the hospital from January 2018 to December 2022 were reviewed.All patients received ^(18)F-FDG SPECT/CT examination and coronary angiography.The different collateral circulation formation degrees,myocardial survival and correlation between myocardial survival and collateral circulation formation were compared.Results:There were 115 diseased vessels in 93 patients with coronary chronic total occlusion.There were no statistically significant differences in the general data and the proportion of patients with myocardial survival among patients with different collateral circulation formation degrees(P>0.05),but there were statistical differences in the viable myocardial area and infarcted myocardial area(P<0.05).Spearman correlation analysis showed that there was no correlation between viable myocardial area,infarcted myocardial area and Rentrop score(P>0.05).Conclusion:The degree of collateral circulation formation in patients with coronary chronic total occlusion is not related to myocardial survival.Preoperative ^(18)F-FDG SPECT/CT myocardial metabolic imaging is of great value to confirm the range of viable myocardium.