环糊精包埋技术研究进展及其在化妆品原料包埋中的应用

Research progress of cyclodextrin encapsulation technology and its application on cosmetic ingredients

环糊精(CDs)是葡萄糖的环状低聚物,它可以封装其他分子。其显著的封装特性导致了一种“主体-客体”类型的关系,它可以修改或改善客体分子的物理、化学或生物特性。其应用几乎适用于所有的工业部门,特别是制药、食品、化学、色谱、催化、生物技术、农业、化妆品、卫生、医药、纺织和环境。同时由于环糊精本身绿色无毒可降解,能够作为一种合适的传输载体被用于化妆品及其相关领域。因此环糊精包埋载体技术也受到了化妆品领域的广泛关注。文章介绍了环糊精包埋物制备方法,表征方法以及其在包埋化妆品相关原料:多酚、黄酮、精油中的应用。

Cyclodextrins are cyclic oligosaccharides that are widely used to improve the performance of bioactive compounds by encapsulation,such as food additives and ingredients or pharmaceutical compounds.Currently,cosmetic industry is constantly striving for better efficacy based on safety.However,the problems of poor water solubility and oxidative decomposition for many active ingredients have greatly limited their development in cosmetic products.Cyclodextrins can protect these compounds against light and oxidative degradation and provide host-guest supramolecular complexes having controlled release properties by molecular encapsulation,enhancing the water solubility and bioavailability.Cyclodextrins are green,non-toxic and degradable and can be used as a suitable delivery vehicle in cosmetics and many other fields.Therefore,the technology by using cyclodextrin as a carrier has also received a lot of attention in the cosmetic field.In recent years,flavonoids and polyphenols have received much attention in the cosmetic industry because of their good whitening and antioxidant effects.Essential oils have also drawn much attention from consumers.In this review,the preparation of cyclodextrin inclusion complexes was introduced,as well as their characterization and their application on many cosmetic ingredients such as polyphenols,flavonoids and essential oils.