围产期易栓症的抗凝治疗

Anticoagulation treatment in the perinatal period for patients with thrombophilia

易栓症会增加妊娠期间及产后发生静脉血栓的风险,并且与反复自然流产、子痫前期、胎儿宫内生长受限等不良妊娠结局相关。本文将结合易栓症人群妊娠期处理相关指南和文献,介绍合并易栓症人群妊娠期及产后预防性抗凝治疗以降低血栓和不良妊娠结局风险的方案选择。

Thrombophilia is associated with an increased risk of venous thromboembolism during pregnancy and the postpartum period,and has been linked to adverse outcomes,such as recurrent spontaneous abortion,preeclampsia and fetal growth restriction.This article will review the relevant guidelines and literature on managing patients with thrombophilia in pregnancy,introducing prophylactic anticoagulation therapy options for patients with thrombophilia during pregnancy and the postpartum period to reduce the risk of thrombosis and adverse pregnancy outcomes.