儿童支气管肺炎并发继发性血小板增多症的临床分析

Clinical analysis of pediatric bronchopneumonia complicated by secondary thrombocytosis

目的通过分析儿童支气管肺炎并发继发性血小板增多症的临床资料,探讨肺炎儿童血小板增多的发病机制、影响因素、临床特征和意义,提高对继发性血小板增多症的认识。方法选取2020年1月至2021年12月广州市妇女儿童医疗中心收治的支气管肺炎并发继发性血小板增多症77例,其中男48例,女性29例,年龄1个月~6岁。回顾性分析其临床资料,总结病原体、性别、年龄、治疗时间、血红蛋白、C反应蛋白、血小板特点等。结果77例支气管肺炎并发继发性血小板增多症患儿中,最常见的病原体为腺病毒(11例)、呼吸道合胞病毒(10例)、支原体(7例);血小板增多和重症肺炎的发生有相关性。结论腺病毒、呼吸道合胞病毒、支原体在引起儿童肺炎并发继发性血小板增多症的机制方面具有一定的相关性。

Objective By analyzing clinical data from pediatric cases of bronchopneumonia complicated by secondary thrombocytosis,to explore the pathogenesis,influencing factors,clinical characteristics,and significance of secondary thrombocytosis in children with pneumonia,and to enhance the understanding of secondary thrombocytosis.Methods A total of 77 cases of thrombocytosis secondary to bronchopneumonia admitted to Guangzhou Women and Children's Medical Center between January 2020 and December 2021 were selected for retrospective analysis,including 48 boys and 29 girls,aged from 1 month to 6 years.The clinical data were analyzed to summarize the pathogens,gender,age,treatment duration,hemoglobin,C-reactive protein,and platelet characteristics.Results Among the 77 children with thrombocytosis secondary to bronchopneumonia,the most common pathogens identified were adenovirus(11 cases),respiratory syncytial virus(10 cases),and mycoplasma(7 cases);there was relevance between thrombocytosis and severe pneumonia.Conclusion Adenovirus,respiratory syncytial virus,and mycoplasma have some relevance in the mechanism of causing secondary thrombocytosis in children with bronchopneumonia.