HIV/AIDS患者治疗依从性自我效能感及相关因素

Influencing factors of self-efficacy for treatment adherence in HIV/AIDS patients

目的调查HIV/AIDS患者治疗依从性自我效能感及其相关因素。方法于2022年5-7月采用方便抽样法纳入杭州某传染病医院感染科门诊840例HIV/AIDS患者作为研究对象,调查内容包括社会人口学特征、生活习惯、疾病相关资料、焦虑抑郁、睡眠障碍、治疗依从性自我效能等,通过多元逐步回归分析影响治疗依从性自我效能感维度1融合和维度2毅力的因素。结果840例HIV/AIDS患者治疗依从性自我效能感较好,治疗依从性自我效能感总分为(111.07±14.54)分,维度1融合评分为(55.44±7.86)分,维度2毅力评分为(55.63±7.61)分。多元逐步回归分析显示,抑郁与HIV/AIDS患者治疗依从性自我效能感维度1融合(β=-0.455,P<0.001)和维度2毅力(β=-0.445,P<0.001)相关。全身慢性疼痛(β=-3.020,P<0.05)、基线CD4细胞计数(β=-0.580,P<0.05)与治疗依从性自我效能感维度2毅力相关。结论改善HIV/AIDS患者抑郁、疼痛等不适症状可以提高HIV/AIDS患者治疗依从性自我效能。

Objective To explore the influencing factors of self-efficacy for treatment adherence among people living with HIV(PLWHs).Methods A total of 840 PLWHs were investigated in the Outpatient Infection Department of one infectious disease hospital in Hangzhou using the convenient sampling method.The survey contents consisted of demographic characteristics,disease characteristics,anxiety and depression,sleep disorders,and self-efficacy for treatment adherence.Stepwise multiple regression analysis was used to analyze the factors affecting the dimensional integration and perseverance of self-efficacy for treatment adherence.Results The total score of self-efficacy for treatment adherence was 111.07±14.54.The scores for dimensional integration and perseverance were 55.44±7.86 and 55.63±7.61,respectively.The results of stepwise multiple regression analysis showed that depression was related to the dimensional integration(β=-0.455,P<0.001)and perseverance(β=-0.445,P<0.001)of the self-efficacy for treatment adherence.In addition,the systemic chronic pain(β=-3.020,P<0.05)and baseline CD4 cell counts(β=-0.580,P<0.05)were associated with the dimensional perseverance of the self-efficacy for treatment adherence.Conclusions The self-efficacy for treatment adherence can be enhanced through efforts to relieve depression,chronic pain,and other symptoms among HIV/AIDS patients.