瘢痕疙瘩的放疗进展

Development of radiotherapy for keloids

放疗是治疗瘢痕疙瘩的一种有效方法,经过多年的临床实践,手术联合放疗的疗效已得到临床医生认可。放疗技术已从浅层X线照射发展到目前的近距离放疗,但最佳放疗策略尚未达成共识。外科术后的放疗时机、放疗剂量、分割方式及病变部位和并发症等因素均不同程度地影响其临床疗效,优化放疗策略有利于降低复发率并提高患者满意度。该文对瘢痕疙瘩的放疗剂量、放疗时机及分割方式等进行了综述,以便于临床医生甄选放疗方案。

Radiotherapy may be an effective method for the treatment of keloids.After decades of clinical practice,the efficacy of radiotherapy combined with surgery has been comprehensively recognized and reported by the clinicians.At presents,radiotherapy has innovated from superficial X-ray to brachytherapy for the treatment of keloids,while the consensus of optimized radiotherapy strategy has not been defined.Many factors such as radiation interval,dose,fractions,lesion locations and complications may affect the clinical outcome of radiotherapy for keloids.Optimizing radiotherapy strategies can help improve the clinical outcome,as well as patient satisfaction,and reduce the recurrence rate of keloids.This article discussed the radiation dose,interval,and fractions of radiotherapy for keloids after extensive review of the existing literature,which may facilitate clinical decision making.