正念认知疗法联合药物治疗对青少年抑郁症患者心理状况及认知功能的影响

Effects of Mindfulness Cognitive Therapy Combined with Drug Therapy on Mental Status and Cognitive Function of Adolescents with Depression

目的 探讨正念认知疗法联合药物治疗对青少年抑郁症患者心理状况及认知功能的影响。方法 选取2020年1月至2021年12月在郑州市第九人民医院接受治疗的94例青少年抑郁症患者作为研究对象,按照随机数字表法分为观察组和对照组,各47例。两组均接受抗抑郁症药物治疗,观察组患者接受正念认知疗法干预8周。采用汉密尔顿抑郁量表(HAMD)和心理健康评定量表(SCL-90)对两组患者心理状态进行评价,采用重复性成套神经心理状态测验(RBANS)对两组患者认知功能进行评价,采用简明健康状况调查表(SF-36)对两组患者生活质量进行评价。结果 治疗8周时,两组HAMD和SCL-90评分降低,且观察组评分低于对照组(P<0.05),RBANS量表中即刻记忆、视觉广度、言语功能、注意力、延迟记忆等维度以及SF-36评分升高,且观察组评分高于对照组(P<0.05)。结论 正念认知疗法联合药物治疗青少年抑郁症,可有效改善患者心理状况及认知功能,提高生活质量。

Objective To explore the effects of mindfulness cognitive therapy combined with drug therapy on mental status and cognitive function of adolescents with depression.Methods A total of 94 adolescent depression patients who received treatment at the Ninth People’s Hospital of Zhengzhou from January 2020 to December 2021 were selected as the research subjects.Patients were divided into observation group and control group according to random number table method,with 47 cases in each group.Both groups received antidepressant medication treatment,while the observation group received mindfulness cognitive therapy intervention for 8 weeks.The Hamilton depression scale(HAMD)and symptom check-list 90(SCL-90)were used to evaluate the mental state,the repeatable battery for the assessment of neuropsye hological status(RBANS)was used to evaluate the cognitive function,and the 36-item short form survey(SF-36)was used to evaluate the quality of life.Results At 8 weeks of treatment,HAMD and SCL-90 scores were reduced in both groups,and the scores in the observation group were lower than those in the control group(P<0.05).At 8 weeks of treatment,the scores of immediate memory,visual span,speech function,attention,delayed memory of the RBANS scale and SF-36 were increased in both groups,and the scores in the observation group were higher than those in the control group(P<0.05).Conclusion Mindfulness cognitive therapy combined with medication can effectively improve the psychological status and cognitive function of adolescents with depression,and improve their quality of life.