ABO异型造血干细胞移植后患者的输血分析

Analysis on blood transfusion after ABO allogeneic hematopoietic stem cell transplantation

目的研究ABO异型造血干细胞移植后患者的临床输血特点。方法分析河南省人民医院2021年1月至2022年7月期间的4例进行异基因造血干细胞移植(allo-HSCT)的ABO血型不合患者,在造血干细胞移植期间,受者在不同时间段的血型变化特征,进而为受者选择合适的血液制品进行输血。结果ABO异型造血干细胞移植后,患者的血型随着移植的时间在逐渐改变,我们根据患者血型变化情况而选择相合的血液成分为患者输注,使得输注安全有效。结论随着ABO异型造血干细胞移植后患者的血型变化,为患者选择相配合的血液成分进行输血,可保证输血安全和有效。

Objective To study the clinical characteristics of blood transfusion after ABO allogeneic hematopoietic stem cell transplantation.Methods Four patients with ABO blood group incompatibility who took allogeneic hematopoietic stem cell transplantation at Henan People's Hospital from January 2021 to July 2022 were analyzed.During the transplantation,the characteristics of blood group changes in the 4 recipients at different time periods were analyzed to select the appropriate blood products for the recipients'blood transfusion.Results After the ABO allogeneic hematopoietic stem cell transplantation,the patients'blood types gradually changed with the time of transplantation.We selected the corresponding blood components for the patients'infusion according to their blood type change,making the infusion safe and effective.Conclusion As the blood group of patients after ABO allogeneic hematopoietic stem cell transplantation changes,we select matching blood components for their blood transfusion to ensure the safety and effectiveness of blood transfusion.