STIC-TUI技术在孕中期胎儿先天性心血管病中的诊断价值

The Diagnostic Value of STIC-TUI Technology in Fetal Congenital Heart Disease in Early-Middle Pregnancy

【目的】探讨四维超声时间空间相关成像和超声断层显像(STIC-TUI)技术在孕中期胎儿先天性心血管病(简称先心病)中的诊断价值。【方法】选取2020年1月至2022年1月在安康市妇幼保健医院进行STIC-TUI和常规二维超声成像检查的80例单胎孕妇作为研究对象,以产后复查结果作为金标准,采用Kappa一致性分析STIC-TUI、常规二维超声单独及联合检查对孕中期胎儿先心病的诊断效能,并比较STIC-TUI技术、常规二维超声检查时间及图像质量评分。【结果】在80例胎儿中发现心脏畸形7例,其中采用STIC-TUI技术检出6例,漏诊1例为房间隔缺损;常规二维彩超检测出5例,漏诊2例为房间隔缺损;产后复查证实患有先心病患儿7例。STIC-TUI技术、常规二维彩超检查及产后复查结果比较,差异无统计学意义(P>0.05);STIC-TUI技术检查时间明显短于常规二维彩超检查时间,差异具有统计学意义(P<0.05);STIC-TUI技术与常规二维彩超图像质量评分比较,差异无统计学意义(P>0.05);一致性分析结果显示:STIC-TUI诊断胎儿先心病的灵敏度为0.714,特异性为0.986,准确性为0.962,Kappa值为0.748;常规二维彩超诊断胎儿先心病的灵敏度为0.571,特异性为0.986,准确性为0.950,Kappa值为0.640;STIC-TUI与常规二维彩超联合诊断胎儿先心病的灵敏度为0.857,特异性为0.986,准确性为0.975,Kappa值为0.843。【结论】STIC-TUI对孕中期胎儿先心病有较好的诊断效能,且STIC-TUI与常规二维彩超联合检查可提高诊断的灵敏度。

【Objective】To exploring the diagnostic efficacy of four-dimensional ultrasound spatiotemporal correlation imaging and ultrasound tomography(STIC-TUI)technology for fetal congenital heart disease in the second trimester of pregnancy(early-middle pregance).【Methods】A total of 80 pregnant women who underwent ultrasound screening in our hospital from January 2020 to January 2022 were selected as the research subjects.All of them received both STIC-TUI and conventional two-dimensional ultrasound imaging examinations.Using the output review results as the gold standard,We used the Kappa to analyze the efficacy of STIC-TUI alone,conventional two-dimensional ultrasound alone,and the combination of the two methods in diagnosing fetal congenital heart disease in the second trimester.Time consumption and image quality scores between STIC-TUI and conventional two-dimensional ultrasound examination were also compared.【Results】Among 80 fetuses,7 cases were found to have cardiac abnormalities.Of which,6 cases were detected using STIC-TUI technology,and 1 was missed in the diagnosis of atrial septal defect;Routine two-dimensional ultrasound detected 5 cases,while missed diagnosis in 2 cases of atrial septal defect.Postpartum follow-up confirmed 7 children with heart disease.The postnatal follow-up result showed there was no significant difference between STIC-TUI technology and conventional two-dimensional ultrasound(P>0.05).However,the STIC-TUI examination time was significantly shorter than the conventional two-dimensional ultrasound examination time,and the difference was statistically significant(P<0.05).There was no significant difference in image quality scores between STIC-TUI and conventional two-dimensional ultrasound(P>0.05).After consistency analysis,the sensitivity of STIC-TUI in diagnosing fetal congenital heart disease was 0.714,the specificity was 0.986,the accuracy was 0.962,and the Kappa value was 0.748;The sensitivity,specificity,accuracy,and Kappa value of conventional two-dimensional ultrasound in diagnosing fetal congenital heart disease are 0.571,0.986,0.950,and 0.640,respectively;The sensitivity,specificity,accuracy,and Kappa value of the combination of STIC-TUI and conventional two-dimensional ultrasound in the diagnosis of fetal congenital heart disease are 0.857,0.986,0.975,and 0.843,respectively.【Conclusion】STIC-TUI can be used to diagnose fetal congenital heart disease in the second trimester of pregnancy with good diagnostic efficacy.Moreover,the combination of STIC-TUI and conventional two-dimensional ultrasound can improve the sensitivity of diagnosis.