未破裂颅内动脉瘤神经心理功能研究进展

Research progress on the neuropsychological function of unruptured intracranial aneurysm

未破裂颅内动脉瘤(unruptured intracranial aneurysm,UIA)患者容易产生焦虑和抑郁不良情绪,部分患者还会出现认知障碍,一定程度上影响患者生活质量。预防性介入治疗和开颅手术是治疗UIA的主要方式,近年来,许多研究报告两种治疗方式对UIA患者焦虑、抑郁不良情绪及认知功能的影响。本文通过综述UIA预防性治疗前后患者神经心理功能变化的研究现状,发现两种治疗方式总体上不会对患者神经心理功能造成长期不良影响,而综合性的干预策略可使患者最大程度受益。

Patients with unruptured intracranial aneurysm(UIA)are prone to anxiety and depressive dysphoria,and some patients may also experience cognitive disorder,which can affect their quality of life to some extent.Preventive interventional treatment and craniotomy are the main modalities for the treatment of UIA.In recent years,many studies have reported the effects of these two treatment strategies on the anxiety,depression and cognitive function of patients with UIA.This paper reviews the current status of research on the changes in neuropsychological function of patients before and after preventive treatment of UIA.Both treatment modalities were found to have no overall long-term adverse effects on patients'neuropsychological function,and Comprehensive intervention strategy maximizes therapeutic benefits.