张莹雯分期辨治三阴性乳腺癌经验

Zhang Yingwen's experience in the syndrome differentiation and treatment of triple-negative breast cancer by stages

三阴性乳腺是一种特殊亚型的乳腺癌,其细胞分化差,恶性程度高,治疗手段较少,治疗后易复发转移,生存期短,预后差,成为近年来研究乳腺癌的热点和难题。张莹雯认为三阴性乳腺癌以脾虚肾亏为本,肝郁气滞为核心病机,痰湿、瘀血、癌毒胶结不解,风邪内生,乘虚侵扰流窜,促进了三阴性乳腺癌的发生、发展和转移。张莹雯分期分型辨治三阴性乳腺癌,疾病早期健脾补肾,增强体质,减轻不良反应;临床观察期疏肝解郁、化痰活血、清热解毒散结、益气养阴;复发转移期滋阴祛风、活血通脉、益气养血、调补肝肾,并自创“抑癌扶正平衡II号方”治疗肿瘤,疗效显著。

Triple-negative breast cancer is a special subtype of breast cancer.Due to its low cell differentiation,high degree of malignancy,fewer treatment methods,easy recurrence and metastasis,short survival period and poor prognosis after treatment,triple-negative breast cancer has become a hot spot and difficult problem in the breast cancer research in recent years.Zhang Yingwen believes that the root cause of the disease is the kidney and spleen deficiency,and its core pathogenesis is the syndrome of liver depression and qi stagnation,while the inextricably bonded phlegmdampness,blood stasis and cancer toxins contribute to the internal birth of wind pathogens,which then assault and move in the body,promoting the occurrence,development and metastasis of triple-negative breast cancer.Professor Zhang treats the disease by stages and on the basis of varying syndromes:strengthening the spleen and kidney at the early stage of the disease,enhancing the physical fitness and reducing its adverse reactions;dispersing stagnated liver qi for relieving qi stagnation,dissipating phlegm and promoting blood circulation,clearing heat,detoxifying and resolving masses,benefiting qi and nourishing yin during its clinical observation period;while in its recurrence and metastasis period,nourishing yin and dispelling wind,promoting blood circulation and unblocking the meridians,benefiting qi and nourishing blood,regulating and tonifying the liver and kidney.She creates her own experiential effective prescription to treat tumors,achieving a significant effect.