马鞍山地区肺癌发病趋势及转归调查

Incidence trend of clinical characteristics and outcome of lungcancer in Ma′anshan District

目的探究马鞍山地区肺癌的发病趋势、临床特征及转归调查。方法选择2018年1月至2022年5月马鞍山市人民医院呼吸与危重症医学科收治的398例肺癌患者资料,分析年龄、性别、组织学、转归资料的构成比及其随时间的变化趋势。结果5年间该地区肺癌患者年龄最小35岁,最大92岁,平均(69.94±9.76)岁;患者集中于70~79岁,其次为60~69岁和>80岁年龄段,发病人数呈逐年递减趋势,鳞状细胞癌患者从集中于60~69岁转移至70~79岁年龄段,腺癌主要集中于70~79岁年龄段。5年间鳞状细胞癌发生率呈上升趋势(P=0.006),腺鳞癌呈下降趋势(P=0.005),肺癌好转出院率逐年递增(P<0.001),治愈出院率(P=0.044)逐年递减,其中男性好转出院率呈逐年上升趋势(P=0.039),女性好转出院率呈下降再上升趋势,其中2020年好转出院率最低(P=0.027),患者死亡率随着年龄上升而增高(P=0.002)。结论马鞍山地区2018—2022年间发病人数呈逐年递减趋势,患者主要集中于70~79岁年龄段,腺癌发病率最高。整体好转出院率逐年递增、治愈出院率逐年递减,男性好转出院率呈逐年上升趋势,女性反之。

Objective To investigate the incidence trend,clinical characteristics and prognosis of lung cancer in Ma′anshan area.Methods The data of 398 lung cancer patients admitted to the Department of Respiratory and Critical Care Medicine,Ma′anshan People′s Hospital in Ma′anshan area from January 2018 to May 2022 were selected,and the composition ratio of age,sex,histology and outcome data and its change trend over time were analyzed.Results The minimum age of lung cancer patients in this area was 35 years old,the maximum age was 92 years old,and the average age was(69.94±9.76)years old.The patients were mainly from 70 to 79 years old,followed by 60 to 69 years old and>80 years old.The number of patients was decreasing year by year.The patients with squamous cell carcinoma transferred from 60 to 69 years old to 70 to 79 years old,and adenocarcinoma mainly concentrated in 70 to 79 years old.The incidence of squamous cell carcinoma increased(P=0.006),while that of adenosquamous carcinoma decreased(P=0.005).The improved discharge rate of lung cancer was increasing year by year(P<0.001),and the cured discharge rate(P=0.044)was decreasing year by year.The improved discharge rate of men was increasing year by year(P=0.039),while the improved discharge rate of women was decreasing and then increasing,and the improved discharge rate in 2020 was the lowest(P=0.027).The mortality increased with age(P=0.002).Conclusion From 2018 to 2022,the number of patients in Ma′anshan area will decrease year by year.The patients were mainly in the 70-79 age group.The incidence rate of adenocarcinoma was the highest,while the incidence rate and age of squamous cell carcinoma were on the rise.The overall improvement discharge rate is increasing year by year,and the cure discharge rate is decreasing year by year.The improvement discharge rate for men is increasing year by year,and vice versa for women.