CT特征预测基于2021年肺肿瘤新分类肺纯磨玻璃结节浸润性及浸润程度的价值

The Value of CT Features in Predicting the Invasion and Degree of Pulmonary Ground Glass Nodules Based on the New Classification of Lung Tumors in 2021

目的探讨CT特征预测基于2021年肺肿瘤新分类肺纯磨玻璃结节浸润性及浸润程度的价值。方法选择2020年1月至2022年8月在某医院接受手术治疗的磨玻璃结节病变的患者286人的数据资料进行回顾性分析。描述全部患者的纯磨玻璃结节病变的病理分型情况。对比纯磨玻璃结节病变不同病理分型患者分组的一般临床资料。对比纯磨玻璃结节病变不同病理分型病灶的CT定性参数。对比纯磨玻璃结节病变不同病理分型病灶的CT定量参数。分析对于纯磨玻璃结节病变的病理分型推断具有价值的参数。结果共有286名患者的数据资料纳入本次研究中,共包括有306个纯磨玻璃结节病变。在全部286名患者之中,腺体前驱病变组117人、微浸润性腺癌组111人、浸润性腺癌组58人,3组患者的一般临床资料的数据差异无统计学意义(P>0.05)。在全部306个纯磨玻璃结节病变中,腺体前驱病变组130个、微浸润性腺癌组116个、浸润性腺癌组60个。3组的CT定性参数对比中,分叶、空泡征、内部血管征的数据差异具有统计学意义(P<0.05)。3组的CT定量参数对比中,平扫CT值的数据差异具有统计学意义(P<0.05)。分叶,空泡征,内部血管征,平扫CT值均是纯磨玻璃结节病变的病理分型的影响因素(OR=3.500,14.125,10.114,1.008,P<0.05)。结论基于2021年肺肿瘤的新分类标准,部分CT检查指标对于肺纯磨玻璃结节浸润性以及浸润程度具有良好的预测价值,这可以为今后患者的早期诊断以及治疗方法选择提供一定的依据。

Objective To explore the value of CT features in predicting the invasion and degree of pulmonary ground glass nodules based on the new classification of lung tumors in 2021.Methods The data of 286 patients with ground glass nodule disease who received surgical treatment in a hospital from January 2020 to August 2022 were selected for retrospective analysis.Describe the pathological classification of pure ground glass nodules in all patients.To compare the general clinical data of patients with pure ground glass nodules with different pathological classifications.To compare the CT qualitative parameters of different pathological types of pure ground glass nodule lesions.To compare CT quantitative parameters of different pathological types of pure ground glass nodule lesions.Analysis of valuable parameters for pathological classification of pure ground glass nodules.Result The data of 286 patients were included in this study,including 306 pure ground glass nodule lesions.Among all 286 patients,117 were in the glandular precursor group,111 in the minimally invasive adenocarcinoma group,and 58 in the invasive adenocarcinoma group.There was no significant difference in the data of general clinical data among the three groups(P>0.05).In all 306 pure ground glass nodule lesions,130 were glandular precursor lesions,116 were minimally invasive adenocarcinoma,and 60 were invasive adenocarcinoma.In the comparison of CT qualitative parameters of the three groups,the data of lobulation,vacuole sign and internal vascular sign were statistically significant(P<0.05).In the comparison of CT quantitative parameters of the three groups,the data difference of plain CT values was statistically significant(P<0.05).Lobation,vacuole sign,internal vascular sign,plain CT value are all factors influencing the pathological classification of pure ground glass nodule lesions(OR=3.500,14.125,10.114,1.008,P<0.05).Conclusion Based on the new classification standard of lung tumors in 2021,some CT findings have good predictive value for the invasion and degree of pulmonary ground glass nodules,which can provide some basis for early diagnosis and treatment of patients in the future.