睡眠时长与中国6~19岁儿童青少年肥胖风险的关系:基于系统综述与Meta分析

The Risk Relationship between Sleep Duration and Childhood Obesity in Chinese Children and Adolescents Aged 6 to 19:A Systematic Review and Meta-Analysis

目的:探讨睡眠时长与中国学龄儿童肥胖之间的风险关系。方法:在3个中文数据库(中国知网、万方数据、维普数据库)和5个英文数据库(Web of Science、PubMed、Embase、Cochrane Library和Medline)中检索截至2019年10月1日前发表的队列和病例对照研究,采用Stata 15.0软件进行Meta分析,运用随机效应模型估计总体比值比(OR)和95%置信区间(CI)。结果:共有14篇文章进入系统综述,其中11篇文献符合Meta分析纳入标准。Meta分析结果显示,睡眠时间偏长使儿童肥胖风险降低40%(OR=0.60;95%CI:0.47,0.76;P<0.01),睡眠时间偏短使儿童肥胖风险增加126%(OR=2.26;95%CI:1.18,4.33;P<0.01)。结论:充足的睡眠有利于预防儿童超重或肥胖。政府相关部门、学校、家庭应制定促进睡眠的干预措施,适当延长儿童青少年的睡眠时间.

Objective:The study uses a systematic review to summarize and analyze relevant studies and explore the risk relationship between sleep duration and childhood obesity in China,and provides a reference for preventing or controlling childhood obesity.Methods:Cohort studies and case-control researches published before October 1,2019 were retrieved from three Chinese databases(CNKI,Wanfang Data and VIP Database)and five English databases(Web of Science,PubMed,Embase,Cochrane Library and Medline).Meta-analysis was performed with Stata 15.0 software.Random effect models were used to estimate the overall odds ratio(OR)and 95%confidence interval(CI).Results:A total of 14 literatures were systematically reviewed,among which 11 literatures met the inclusion criteria of Meta-analysis.Meta-analysis results showed that long sleep reduced the risk of childhood obesity by 40%(OR=0.60;95%CI:0.47,0.76;P<0.01)whereas short sleep duration was associated with a 126%increased risk in children(OR=2.26;95%CI:1.18,4.33;P<0.01).Conclusions:Long sleep can decrease the risk of obesity in children in China.Therefore,effort should be made by government,schools,and families to take actions to extend sleep time of children and adolescents in China.