丙硫菌唑合成工艺研究进展

Research Progress on Synthesis Process of Prothioconazole

丙硫菌唑是新型三唑硫酮类杀菌剂,具有作用机制独特、内吸性良好和杀菌谱广等特点,可用于多种农作物的病害防治。但是丙硫菌唑的合成工艺路线多、步骤长、合成难度大,给工艺路线的选择带来了一定的困难。介绍了丙硫菌唑基于不同原料和反应的合成工艺,分析了工艺特点及最新进展,以便工艺选择时参考。

Prothioconazole is a new triazolethione fungicide with unique mechanism of action,good internal absorption and broad bactericidal spectrum.It can be used for disease control of a variety of crops.However,the synthesis of propionazole has many process routes,long steps and difficult synthesis,which brings some difficulties to the selection of process routes.The synthetic process of propionazole based on different raw materials and reactions are introduced.The process characteristics and the latest progress are analyzed for reference in procedure selection.