摘要
Researchers have identified a novel function of acetylcholine produced by spleen fibroblastic reticular cells(FRCs)in driving autoimmune responses in systemic lupus erythematosus(SLE),according to a new study published in Cell Metabolism recently.1 The study links the neurotransmitter acetylcholine to the lipid metabolism of autoreactive B cells in the pathogenesis of SLE.