摘要
衰老是随着增龄出现的组织器官功能性衰退过程,伴随着多种老年相关性疾病的发生。热量限制(CR)作为一种重要的饮食干预方式,参与了衰老过程,并且可以明显改善老年高血压、糖尿病、阿尔茨海默病、肌少症以及衰弱等多种老年相关疾病的发生及发展。本文综述CR对衰老和老年相关疾病影响的研究进展,为CR的临床应用和推广提供依据。
Senescence is a physiological process characterized by a progressive decline in tissue and organ function as individuals age.With advancing age,the occurrence of various age-related diseases often coincides with senescence.Caloric restriction(CR),a dietary intervention,has been closely associated with senescence and has demonstrated remarkable potential in the prevention and amelioration of numerous age-related conditions,such as hypertension,diabetes mellitus,Alzheimer's disease,sarcopenia,and asthenia.This comprehensive literature review explores the profound impact of CR on senescence and age-related diseases,aiming to provide robust evidence to support the clinical application of CR as a promising therapeutic strategy.
作者
胡鑫
李优磊
高天雅
李昕
王晓明
侯莉明
Hu Xin;Li Youei;Gao Tianya;Li Xin;Wang Xiaoming;Hou Liming(Medical College of Yan'an University,Yan'an 716000;Department of Geriatrics,Xijing Hospital,Airforce Medical University,Xi'an 710000)
出处
《国际老年医学杂志》
2023年第4期493-496,共4页
International Journal of Geriatrics
基金
国家重点研发计划项目(2020YFC2008000)。
关键词
热量限制
衰老
老年疾病
Caloric restriction
Senility
Geriatric disease