热应激影响奶牛胚胎发育作用机制的研究进展

Research Progress on the Mechanism of Heat Stress Affecting the Development of Dairy Cow Embryos

奶牛热应激是高温环境引起的奶牛生理上的非特异性反应,会严重影响奶牛自身生理状态,损害胚胎发育,进而造成巨大经济损失。因此,如何提高热应激条件下奶牛胚胎发育能力,对于促进奶牛养殖业健康发展意义重大。本文就热应激对奶牛内分泌、卵母细胞及胚胎的负面影响,以及物理降温、激素治疗、添加IGF1、基因编辑技术修饰HSPA1L和PRLR基因等解决措施进行综述,为促进热应激奶牛胚胎发育提供一定参考。

Heat stress of dairy cows is a non-specific physiological reaction caused by high tempera-ture environment,which can seriously affect the physiological state and embryonic development of dairy cows,and then cause huge economic losses.Therefore,how to improve the development ability of dairy cow embryos under heat stress is of great significance to promote the healthy development of dairy cattle breeding industry.In this paper,the negative effects of heat stress on endocrine,oocytes and embryos of dairy cows,as well as the solution measures such as physical cooling,hormone therapy,addition of IGF1,modification of HSPA 1L and PRLR genes by gene editing technology were reviewed,so as to provide some reference for improving the develop-ment ability of dairy cow embryos under heat stress.